Oxime of 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one

Base Information

• Chemical Name: Oxime of 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one
• CAS No.: 146307-43-9
• Molecular Formula: C₂₈H₂₁NO₃
• Molecular Weight: 419.48
• Mol file: 146307-43-9.mol

Synonyms:Oxime of 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one

Chemical Property of Oxime of 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of Oxime of 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one

There total 1 articles about Oxime of 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one (146307-40-6) → Oxime of 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one (146307-43-9) + Ethyl 2-(1'-(4-methoxyphenyl)-naphtho<2,1-b>pyrrol-2'-yl)cinnamate (146307-42-8)

Guidance literature:

With hydrogenchloride; hydroxylamine hydrochloride; acrylonitrile; In tetrahydrofuran; ethanol; for 48h; Heating;

DOI:10.1016/S0040-4020(01)80513-5

Reference yield: 100.0%

ethanol (64-17-5) + Oxime of 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one (146307-43-9) → Ethyl 2-(1'-(4-methoxyphenyl)-naphtho<2,1-b>pyrrol-2'-yl)cinnamate (146307-42-8)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; for 24h; Heating;

DOI:10.1016/S0040-4020(01)80513-5

Reference yield: 1.0%

Oxime of 1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one (146307-43-9) + 2-Chloroacrylonitrile (920-37-6) → 1'-(4-Methoxyphenyl)-1',3'-(1''-chloro-1''-cyanomethano)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>pyrrol)-2-one (146307-46-2)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; for 48h; Heating;

DOI:10.1016/S0040-4020(01)80513-5

upstream raw materials:

1'-(4-methoxyphenyl)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>furan)-2-one

Downstream raw materials:

Ethyl 2-(1'-(4-methoxyphenyl)-naphtho<2,1-b>pyrrol-2'-yl)cinnamate

1'-(4-Methoxyphenyl)-1',3'-(1''-chloro-1''-cyanomethano)-spiro(naphthalene-1(2H),2'(1'H)-naphtho<2,1-b>pyrrol)-2-one