Technology Process of 3-azido-1,2,5-tri-O-benzyl-3,6-dideoxyidose
There total 7 articles about 3-azido-1,2,5-tri-O-benzyl-3,6-dideoxyidose which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
lithium azide;
In
N,N-dimethyl-formamide;
at 0 ℃;
for 1.5h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) NaH, 2.) Bu4NF / 1.) DMF, RT, 3 h, 2.) THF, 45 deg C, 2.5 h
2: 60 percent / diisopropylethylamine / CH2Cl2 / 0.08 h / -10 °C
3: 91 percent / LiN3 / dimethylformamide / 1.5 h / 0 °C
With
lithium azide; tetrabutyl ammonium fluoride; sodium hydride; N-ethyl-N,N-diisopropylamine;
In
dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: imidazole / dimethylformamide / 8.5 h / Ambient temperature
2: 72 percent / N-methylmorpholine N-oxide, OsO4 / acetone; H2O / 1.) 0 deg C, 17 h, 2.) RT, 30 h
3: 94 percent / diisobutylaluminum hydride / CH2Cl2 / -78 °C
4: 1.) NaH, 2.) Bu4NF / 1.) DMF, RT, 3 h, 2.) THF, 45 deg C, 2.5 h
5: 60 percent / diisopropylethylamine / CH2Cl2 / 0.08 h / -10 °C
6: 91 percent / LiN3 / dimethylformamide / 1.5 h / 0 °C
With
1H-imidazole; osmium(VIII) oxide; lithium azide; tetrabutyl ammonium fluoride; sodium hydride; diisobutylaluminium hydride; 4-methylmorpholine N-oxide; N-ethyl-N,N-diisopropylamine;
In
dichloromethane; water; N,N-dimethyl-formamide; acetone;
