4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1 (3-trifluoromethylphenyl)butane-1,4-dione

Base Information

Chemical Name:4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1 (3-trifluoromethylphenyl)butane-1,4-dione
CAS No.:188345-17-7
Molecular Formula:C₂₉H₂₇F₃N₂O₄
Molecular Weight:524.54
Hs Code.:

Synonyms:4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1 (3-trifluoromethylphenyl)butane-1,4-dione

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Chemical Property of 4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1 (3-trifluoromethylphenyl)butane-1,4-dione

Chemical Property:

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Technology Process of 4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1 (3-trifluoromethylphenyl)butane-1,4-dione

There total 2 articles about 4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1 (3-trifluoromethylphenyl)butane-1,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 188345-22-4
2-pyridin-4-yl-1-(3-trifluoromethyl-phenyl)-ethanone

: 85475-10-1
4-(2-chloroacetyl)piperidine-1-carboxylic acid benzyl ester

: 188345-17-7
4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1 (3-trifluoromethylphenyl)butane-1,4-dione

: 271247-39-3
C₃₀H₂₈F₃NO₄

Guidance literature:: 2-pyridin-4-yl-1-(3-trifluoromethyl-phenyl)-ethanone; With sodium hydride; In dimethyl sulfoxide; at 20 ℃; for 1h;

4-(2-chloroacetyl)piperidine-1-carboxylic acid benzyl ester; In dimethyl sulfoxide; at 20 ℃; for 18h;

Reference yield:

: 502639-28-3
4-(3-pyridin-4-yl-acryloyl)-piperidine-1-carboxylic acid benzyl ester

: 454-89-7
3-Trifluoromethylbenzaldehyde

: 188345-17-7
4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1 (3-trifluoromethylphenyl)butane-1,4-dione

Guidance literature:: With NaCN; In ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 188345-17-7
4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1 (3-trifluoromethylphenyl)butane-1,4-dione

: 271247-40-6
3-(3-trifluoromethylphenyl)-4-(pyridin-4-yl)-6-(N-carbobenzoxypiperidin-4-yl)pyridazine

Guidance literature:: 4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1 (3-trifluoromethylphenyl)butane-1,4-dione; With hydrazine; In ethanol; for 4h;

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In toluene; for 0.5h;