C₂₉H₃₄ClN₇O₃S

Base Information

• Chemical Name: C₂₉H₃₄ClN₇O₃S
• CAS No.: 909253-25-4
• Molecular Formula: C₂₉H₃₄ClN₇O₃S
• Molecular Weight: 596.153
• Mol file: 909253-25-4.mol

Synonyms:C₂₉H₃₄ClN₇O₃S

Chemical Property of C₂₉H₃₄ClN₇O₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₉H₃₄ClN₇O₃S

There total 8 articles about C₂₉H₃₄ClN₇O₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 1-(1-ethoxyethyl)-3-[4-(4-methylpiperazin-1-yl)benzoylamino]-1H-thieno[2,3-c]pyrazole-5-carboxylate (909253-24-3) + N1-(p-chlorophenyl)-N1-methylhydrazine (52263-26-0) → C29H34ClN7O3S (909253-25-4)

Guidance literature:

ethyl 1-(1-ethoxyethyl)-3-[4-(4-methylpiperazin-1-yl)benzoylamino]-1H-thieno[2,3-c]pyrazole-5-carboxylate; With trimethylaluminum; In toluene; at 0 - 25 ℃; for 0.5h;

N₁-(p-chlorophenyl)-N₁-methylhydrazine; In toluene; at 50 ℃; for 2.5h;

With potassium phosphate; In toluene; at 25 ℃; for 1h;

Reference yield:

para-dichlorobenzene (106-46-7,84348-21-0) → C29H34ClN7O3S (909253-25-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium hydroxide / palladium diacetate; 2-(dicyclohexylphosphino)-2'-methylbiphenyl / tert-Amyl alcohol / 25 - 100 °C

2.1: potassium hexamethylsilazane / tetrahydrofuran / 0.5 h / -10 °C

2.2: 4 h / -10 - 25 °C

3.1: hydrogenchloride; water / tetrahydrofuran / 16 h / 50 °C

4.1: trimethylaluminum / toluene / 0.5 h / 0 - 25 °C

4.2: 2.5 h / 50 °C

4.3: 1 h / 25 °C

With hydrogenchloride; sodium hydroxide; water; trimethylaluminum; potassium hexamethylsilazane; palladium diacetate; 2-(dicyclohexylphosphino)-2'-methylbiphenyl; In tetrahydrofuran; tert-Amyl alcohol; toluene;

Reference yield:

3,5-dibromo-1-(1-ethoxyethyl)-1H-pyrazole-4-carbaldehyde (888484-98-8) → C29H34ClN7O3S (909253-25-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium carbonate / ethanol / 2 h / Heating / reflux

2.1: potassium phosphate; copper(l) iodide; N,N`-dimethylethylenediamine / 1,4-dioxane / 24 h / 110 °C

3.1: trimethylaluminum / toluene / 0.5 h / 0 - 25 °C

3.2: 2.5 h / 50 °C

3.3: 1 h / 25 °C

With potassium phosphate; copper(l) iodide; trimethylaluminum; sodium carbonate; N,N`-dimethylethylenediamine; In 1,4-dioxane; ethanol; toluene;

upstream raw materials:

ethyl 1-(1-ethoxyethyl)-3-[4-(4-methylpiperazin-1-yl)benzoylamino]-1H-thieno[2,3-c]pyrazole-5-carboxylate

N₁-(p-chlorophenyl)-N₁-methylhydrazine

1-methyl-piperazine

3-bromo-1-(1-ethoxyethyl)-1H-thieno[2,3-c]pyrazole-5-carboxylic acid ethyl ester

Downstream raw materials:

N-{5-[N'-(4-chlorophenyl)-N'-methylhydrazinocarbonyl]-1H-thieno[2,3-c]pyrazol-3-yl}-4-(4-methylpiperazin-1-yl)benzamide