decanoic acid 3-acetoxy-2-(toluene-4-sulfonyloxy)-propyl ester

Base Information

• Chemical Name: decanoic acid 3-acetoxy-2-(toluene-4-sulfonyloxy)-propyl ester
• CAS No.: 314266-03-0
• Molecular Formula: C₂₂H₃₄O₇S
• Molecular Weight: 442.574
• Mol file: 314266-03-0.mol

Synonyms:decanoic acid 3-acetoxy-2-(toluene-4-sulfonyloxy)-propyl ester

Chemical Property of decanoic acid 3-acetoxy-2-(toluene-4-sulfonyloxy)-propyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of decanoic acid 3-acetoxy-2-(toluene-4-sulfonyloxy)-propyl ester

There total 2 articles about decanoic acid 3-acetoxy-2-(toluene-4-sulfonyloxy)-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1-decanoic acid (334-48-5) + acetic acid 3-hydroxy-2-(toluene-4-sulfonyloxy)-propyl ester (309915-61-5) → decanoic acid 3-acetoxy-2-(toluene-4-sulfonyloxy)-propyl ester (314266-03-0)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1080/00397910008087042

Reference yield:

1,3-dioxan-5-yl 4-methylbenzene-1-sulfonate (32061-16-8) → decanoic acid 3-acetoxy-2-(toluene-4-sulfonyloxy)-propyl ester (314266-03-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / TFAA; BF₃*Et₂O / tetrahydrofuran / 2 h / 20 °C

2: 94 percent / DCC; DMAP / CH₂Cl₂ / 1 h / 20 °C

With dmap; boron trifluoride diethyl etherate; dicyclohexyl-carbodiimide; trifluoroacetic anhydride; In tetrahydrofuran; dichloromethane; 1: acylolysis / 2: Esterification;

DOI:10.1080/00397910008087042

upstream raw materials:

1-decanoic acid

acetic acid 3-hydroxy-2-(toluene-4-sulfonyloxy)-propyl ester

1,3-dioxan-5-yl 4-methylbenzene-1-sulfonate

Refernces