4-(1H-Imidazol-1-yl)-3-(trifluoromethyl)aniline hydrochloride

Base Information

Chemical Name:4-(1H-Imidazol-1-yl)-3-(trifluoromethyl)aniline hydrochloride
CAS No.:351324-53-3
Molecular Formula:C₁₀H₈F₃N₃
Molecular Weight:227.189
Hs Code.:
DSSTox Substance ID:DTXSID801221754

Synonyms:351324-53-3;4-imidazolyl-3-(trifluoromethyl)phenylamine;4-imidazol-1-yl-3-(trifluoromethyl)aniline;4-(1H-Imidazol-1-yl)-3-(trifluoromethyl)aniline hydrochloride;SCHEMBL994454;4-(1H-Imidazol-1-yl)-3-(trifluoromethyl)benzenamine;NFQIZPWJBUGGII-UHFFFAOYSA-N;DTXSID801221754;AKOS010149727

Suppliers and Price of 4-(1H-Imidazol-1-yl)-3-(trifluoromethyl)aniline hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-(1H-Imidazol-1-yl)-3-(trifluoromethyl)anilinehydrochloride 97%
5g
$ 752.00

Total 1 raw suppliers

Chemical Property of 4-(1H-Imidazol-1-yl)-3-(trifluoromethyl)aniline hydrochloride

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:227.06703175
Heavy Atom Count:16
Complexity:244

Purity/Quality:: 4-(1H-Imidazol-1-yl)-3-(trifluoromethyl)anilinehydrochloride 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1N)C(F)(F)F)N2C=CN=C2

Technology Process of 4-(1H-Imidazol-1-yl)-3-(trifluoromethyl)aniline hydrochloride

There total 3 articles about 4-(1H-Imidazol-1-yl)-3-(trifluoromethyl)aniline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 351324-52-2
1-<4-nitro-2-(trifluoromethyl)phenyl>-1H-imidazole

: 351324-53-3
4-(1H-imidazol-1-yl)-3-(trifluoromethyl)benzamine

Guidance literature:: With hydrogen; platinum(IV) oxide;
DOI:10.1021/jm00071a002

Reference yield:

: 400-74-8
2-Fluoro-5-nitrobenzotrifluoride

: 351324-53-3
4-(1H-imidazol-1-yl)-3-(trifluoromethyl)benzamine

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylsulfoxide / 25.5 h / 105 - 110 °C

2: H₂ / PtO₂

With hydrogen; potassium carbonate; platinum(IV) oxide; In dimethyl sulfoxide;
DOI:10.1021/jm00071a002