(+/-)-4-<<3-(phosphonomethyl)phenyl>methyl>-2-piperazinecarboxylic acid dihydrochloride

Base Information

Chemical Name:(+/-)-4-<<3-(phosphonomethyl)phenyl>methyl>-2-piperazinecarboxylic acid dihydrochloride
CAS No.:129365-40-8
Molecular Formula:C₁₃H₁₉N₂O₅P*2ClH
Molecular Weight:387.2
Hs Code.:

Synonyms:(+/-)-4-<<3-(phosphonomethyl)phenyl>methyl>-2-piperazinecarboxylic acid dihydrochloride

Suppliers and Price of (+/-)-4-<<3-(phosphonomethyl)phenyl>methyl>-2-piperazinecarboxylic acid dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (+/-)-4-<<3-(phosphonomethyl)phenyl>methyl>-2-piperazinecarboxylic acid dihydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+/-)-4-<<3-(phosphonomethyl)phenyl>methyl>-2-piperazinecarboxylic acid dihydrochloride

There total 2 articles about (+/-)-4-<<3-(phosphonomethyl)phenyl>methyl>-2-piperazinecarboxylic acid dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 4-[3-(Diethoxy-phosphorylmethyl)-benzyl]-piperazine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester

: 129365-40-8
(+/-)-4-<<3-(phosphonomethyl)phenyl>methyl>-2-piperazinecarboxylic acid dihydrochloride

Guidance literature:: With hydrogenchloride; for 22h; Heating;
DOI:10.1021/jm00172a037

Reference yield:

: 126937-44-8
2-methyl 1-phenylmethyl 1,2-piperazinedicarboxilate, trifluoroacetate

: 129365-40-8
(+/-)-4-<<3-(phosphonomethyl)phenyl>methyl>-2-piperazinecarboxylic acid dihydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Na₂CO₃ / 1.) MeOH, 25 deg C, 30 min, 2.) reflux, 2 h

2: 74 percent / 6 M aq. HCl / 22 h / Heating

With hydrogenchloride; sodium carbonate;
DOI:10.1021/jm00172a037