methyl 4-[({[4-cyano-3-(4-nitrophenyl)isothiazol-5-yl]amino}carbonyl)amino]butanoate

Base Information

Chemical Name:methyl 4-[({[4-cyano-3-(4-nitrophenyl)isothiazol-5-yl]amino}carbonyl)amino]butanoate
CAS No.:1446247-82-0
Molecular Formula:C₁₆H₁₅N₅O₅S
Molecular Weight:389.392
Hs Code.:

Synonyms:methyl 4-[({[4-cyano-3-(4-nitrophenyl)isothiazol-5-yl]amino}carbonyl)amino]butanoate

Suppliers and Price of methyl 4-[({[4-cyano-3-(4-nitrophenyl)isothiazol-5-yl]amino}carbonyl)amino]butanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-[({[4-cyano-3-(4-nitrophenyl)isothiazol-5-yl]amino}carbonyl)amino]butanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 4-[({[4-cyano-3-(4-nitrophenyl)isothiazol-5-yl]amino}carbonyl)amino]butanoate

There total 6 articles about methyl 4-[({[4-cyano-3-(4-nitrophenyl)isothiazol-5-yl]amino}carbonyl)amino]butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 605661-28-7
5-amino-3-(4-nitrophenyl)isothiazole-4-carbonitrile

: 27678-30-4
4-isocyanatobutyric acid methyl ester

: 1446247-82-0
methyl 4-[({[4-cyano-3-(4-nitrophenyl)isothiazol-5-yl]amino}carbonyl)amino]butanoate

Guidance literature:: 5-amino-3-(4-nitrophenyl)isothiazole-4-carbonitrile; With potassium carbonate; In tetrahydrofuran; dimethyl sulfoxide; at 20 ℃; for 0.25h;

4-isocyanatobutyric acid methyl ester; In tetrahydrofuran; dimethyl sulfoxide; at 20 ℃;

Reference yield:

: 605661-26-5
2-[amino(4-nitrophenyl)methylene]malononitrile

: 1446247-82-0
methyl 4-[({[4-cyano-3-(4-nitrophenyl)isothiazol-5-yl]amino}carbonyl)amino]butanoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: O,O-Diethyl hydrogen phosphorodithioate / ethanol; water / 100 °C / Inert atmosphere

2.1: dihydrogen peroxide / ethanol / 22 h / Inert atmosphere

3.1: potassium carbonate / tetrahydrofuran; dimethyl sulfoxide / 0.25 h / 20 °C

3.2: 20 °C

With dihydrogen peroxide; potassium carbonate; O,O-Diethyl hydrogen phosphorodithioate; In tetrahydrofuran; ethanol; water; dimethyl sulfoxide;

Reference yield:

: 909028-96-2
3-amino-3-(4-nitrophenyl)-2-thioformamidoacrylonitrile

: 1446247-82-0
methyl 4-[({[4-cyano-3-(4-nitrophenyl)isothiazol-5-yl]amino}carbonyl)amino]butanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: dihydrogen peroxide / ethanol / 22 h / Inert atmosphere

2.1: potassium carbonate / tetrahydrofuran; dimethyl sulfoxide / 0.25 h / 20 °C

2.2: 20 °C

With dihydrogen peroxide; potassium carbonate; In tetrahydrofuran; ethanol; dimethyl sulfoxide;