α,α-diphenyl-4-methoxysalicyl alcohol

Base Information

• Chemical Name: α,α-diphenyl-4-methoxysalicyl alcohol
• CAS No.: 53694-69-2
• Molecular Formula: C₂₀H₁₈O₃
• Molecular Weight: 306.361
• Mol file: 53694-69-2.mol

Synonyms:α,α-diphenyl-4-methoxysalicyl alcohol

Chemical Property of α,α-diphenyl-4-methoxysalicyl alcohol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α,α-diphenyl-4-methoxysalicyl alcohol

There total 5 articles about α,α-diphenyl-4-methoxysalicyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-methoxymethylsalicylate (5446-02-6) + phenyllithium (591-51-5) → α,α-diphenyl-4-methoxysalicyl alcohol (53694-69-2)

Guidance literature:

In tetrahydrofuran; at -78 - 20 ℃; for 3h;

DOI:10.1021/jo8008275

Reference yield:

4-hydroxysalicylic acid (89-86-1) → α,α-diphenyl-4-methoxysalicyl alcohol (53694-69-2)

Guidance literature:

Multi-step reaction with 3 steps

1: NaOH-solution / folgendes Verseifen

2: hydrogen chloride

With hydrogenchloride; sodium hydroxide;

Reference yield:

4-methoxysalicylic acid (2237-36-7) → α,α-diphenyl-4-methoxysalicyl alcohol (53694-69-2)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogen chloride

With hydrogenchloride;

upstream raw materials:

ethyl 2-hydroxy-4-methoxybenzoate

4-hydroxysalicylic acid

4-methoxysalicylic acid

4-methoxymethylsalicylate

Downstream raw materials:

C₂₉H₂₆O₃

6-benzhydrylidene-3-methoxy-cyclohexa-2,4-dienone

water

Refernces