Technology Process of 3-(N-dodecyl-2-hydroxyacetamido)phenyl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate
There total 3 articles about 3-(N-dodecyl-2-hydroxyacetamido)phenyl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3-(dodecylamino)phenyl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate; Acetoxyacetyl chloride;
With
triethylamine;
In
dichloromethane;
for 0 - 20h;
Inert atmosphere;
With
potassium carbonate;
In
methanol; dichloromethane; water;
at 20 ℃;
Inert atmosphere;
DOI:10.1021/ol302748h
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: palladium diacetate; 4a,9a-dihydro-9,9-dimethyl-4,5-bis(diphenylphosphino)-xanthene; potassium phosphate; toluene / 24 h / 110 °C / Inert atmosphere; Molecular sieve; Microwave irradiation
2.1: triethylamine / dichloromethane / 0 - 20 h / Inert atmosphere
2.2: 20 °C / Inert atmosphere
With
potassium phosphate; 4a,9a-dihydro-9,9-dimethyl-4,5-bis(diphenylphosphino)-xanthene; palladium diacetate; triethylamine; toluene;
In
dichloromethane;
DOI:10.1021/ol302748h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine / dichloromethane / 16 h / 20 °C / Inert atmosphere
2.1: palladium diacetate; 4a,9a-dihydro-9,9-dimethyl-4,5-bis(diphenylphosphino)-xanthene; potassium phosphate; toluene / 24 h / 110 °C / Inert atmosphere; Molecular sieve; Microwave irradiation
3.1: triethylamine / dichloromethane / 0 - 20 h / Inert atmosphere
3.2: 20 °C / Inert atmosphere
With
potassium phosphate; 4a,9a-dihydro-9,9-dimethyl-4,5-bis(diphenylphosphino)-xanthene; palladium diacetate; triethylamine; toluene;
In
dichloromethane;
DOI:10.1021/ol302748h
