4-Piperazin-1-yl-3-(trifluoromethyl)aniline

Base Information

Chemical Name:4-Piperazin-1-yl-3-(trifluoromethyl)aniline
CAS No.:319474-60-7
Molecular Formula:C11H14 F3 N3
Molecular Weight:245.247
Hs Code.:
DSSTox Substance ID:DTXSID80363908
Wikidata:Q82147649
Mol file:319474-60-7.mol

Synonyms:319474-60-7;4-piperazin-1-yl-3-(trifluoromethyl)aniline;4-(1-PIPERAZINYL)-3-TRIFLUOROMETHYLBENZENAMINE;Benzenamine,4-(1-piperazinyl)-3-(trifluoromethyl)-;4-(piperazin-1-yl)-3-(trifluoromethyl)aniline;SCHEMBL5252902;DTXSID80363908;GS1559;AKOS011412215;4-(piperazin-1-yl)-3-trifluoromethylaniline

Suppliers and Price of 4-Piperazin-1-yl-3-(trifluoromethyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-(1-PIPERAZINYL)-3-TRIFLUOROMETHYLBENZENAMINE 98.00%
5MG
$ 500.56

Total 6 raw suppliers

Chemical Property of 4-Piperazin-1-yl-3-(trifluoromethyl)aniline

Chemical Property:

Vapor Pressure:6.22E-06mmHg at 25°C
Refractive Index:1.521
Boiling Point:378.6°Cat760mmHg
Flash Point:182.8°C
PSA：41.29000
Density:1.267g/cm³
LogP:2.67220
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:245.11398195
Heavy Atom Count:17
Complexity:251

Purity/Quality:

98% ^*data from raw suppliers

4-(1-PIPERAZINYL)-3-TRIFLUOROMETHYLBENZENAMINE 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)C2=C(C=C(C=C2)N)C(F)(F)F

Technology Process of 4-Piperazin-1-yl-3-(trifluoromethyl)aniline

There total 2 articles about 4-Piperazin-1-yl-3-(trifluoromethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: benzyl 4-(4-nitro-2-(trifluoromethyl)phenyl)piperazine-1-carboxylate

: 319474-60-7
4-(piperazin-1-yl)-3-(trifluoromethyl)aniline

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; for 2h;

Reference yield:

: 400-74-8
2-Fluoro-5-nitrobenzotrifluoride

: 319474-60-7
4-(piperazin-1-yl)-3-(trifluoromethyl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / dimethyl sulfoxide / 120 °C

2: palladium 10% on activated carbon; hydrogen / methanol / 2 h

With palladium 10% on activated carbon; hydrogen; caesium carbonate; In methanol; dimethyl sulfoxide;