(2R)-2-benzyl-3-<<(2-pyridin-4-ylethyl)methylamino>carbonyl>propionic acid

Base Information

Chemical Name:(2R)-2-benzyl-3-<<(2-pyridin-4-ylethyl)methylamino>carbonyl>propionic acid
CAS No.:136010-72-5
Molecular Formula:C₁₉H₂₂N₂O₃
Molecular Weight:326.395
Hs Code.:

Synonyms:(2R)-2-benzyl-3-<<(2-pyridin-4-ylethyl)methylamino>carbonyl>propionic acid

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Chemical Property of (2R)-2-benzyl-3-<<(2-pyridin-4-ylethyl)methylamino>carbonyl>propionic acid

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Technology Process of (2R)-2-benzyl-3-<<(2-pyridin-4-ylethyl)methylamino>carbonyl>propionic acid

There total 4 articles about (2R)-2-benzyl-3-<<(2-pyridin-4-ylethyl)methylamino>carbonyl>propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 136010-71-4
benzyl (2R)-2-benzyl-3-<<(2-pyridin-4-ylethyl)methylamino>carbonyl>propionate

: 136010-72-5
(2R)-2-benzyl-3-<<(2-pyridin-4-ylethyl)methylamino>carbonyl>propionic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 2h;
DOI:10.1021/jm00056a006

Reference yield:

: 55496-55-4
4-(2-methylaminoethyl)pyridine

: 136010-72-5
(2R)-2-benzyl-3-<<(2-pyridin-4-ylethyl)methylamino>carbonyl>propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: N-methylmorpholine / CH₂Cl₂ / 2.25 h / -10 - 20 °C

2: 100 percent / H₂ / 10percent Pd/C / methanol / 2 h

With 4-methyl-morpholine; hydrogen; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/jm00056a006

Reference yield:

: 116129-80-7
(3R)-3-Benzyloxycarbonyl-3-phenylmethylpropionic acid

: 136010-72-5
(2R)-2-benzyl-3-<<(2-pyridin-4-ylethyl)methylamino>carbonyl>propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: N-methylmorpholine / CH₂Cl₂ / 0.08 h / -10 °C

2: N-methylmorpholine / CH₂Cl₂ / 2.25 h / -10 - 20 °C

3: 100 percent / H₂ / 10percent Pd/C / methanol / 2 h

With 4-methyl-morpholine; hydrogen; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/jm00056a006