D-xylo-Hexitol, 2,5-anhydro-1,4,6-trideoxy-1,6-epithio-3-O-methyl- (9CI)

Base Information

• Chemical Name: D-xylo-Hexitol, 2,5-anhydro-1,4,6-trideoxy-1,6-epithio-3-O-methyl- (9CI)
• CAS No.: 316376-08-6
• Molecular Formula: C₇H₁₂O₂S
• Molecular Weight: 160.237
• Mol file: 316376-08-6.mol

Synonyms:D-xylo-Hexitol, 2,5-anhydro-1,4,6-trideoxy-1,6-epithio-3-O-methyl- (9CI)

Chemical Property of D-xylo-Hexitol, 2,5-anhydro-1,4,6-trideoxy-1,6-epithio-3-O-methyl- (9CI)

Chemical Property:

• PSA: 43.76000
• LogP: 0.90570

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of D-xylo-Hexitol, 2,5-anhydro-1,4,6-trideoxy-1,6-epithio-3-O-methyl- (9CI)

There total 2 articles about D-xylo-Hexitol, 2,5-anhydro-1,4,6-trideoxy-1,6-epithio-3-O-methyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,6:2,5-dianhydro-4-deoxy-1-thio-D-xylo-hexitol (231299-45-9) + methyl iodide (74-88-4) → 1,6:2,5-dianhydro-4-deoxy-3-O-methyl-1-thio-D-xylo-hexitol (316376-08-6)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

DOI:10.1016/S0008-6215(00)00190-7

Reference yield:

1,6:2,5-dianhydro-4-deoxy-1-thio-D-erythro-hex-3-ulose (316376-07-5) → 1,6:2,5-dianhydro-4-deoxy-3-O-methyl-1-thio-D-xylo-hexitol (316376-08-6)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄ / ethanol / 0.5 h / 20 °C

2: 1.91 g / NaH / dimethylformamide / 1 h / 20 °C

With sodium tetrahydroborate; sodium hydride; In ethanol; N,N-dimethyl-formamide;

DOI:10.1016/S0008-6215(00)00190-7

Reference yield:

1,6:2,5-dianhydro-4-deoxy-3-O-methyl-1-thio-D-xylo-hexitol (316376-08-6) → 40cyanophenyl 3-S-(4-cyanophenyl)-2,6-thioanhydro-4-deoxy-2,3-dithio-β-D-arabino-hexopyranoside

Guidance literature:

Multi-step reaction with 2 steps

1.1: 100 percent / aq. H₂O₂ / acetic acid / 20 °C

2.1: Ac₂O / 5 h / 100 °C

2.2: 0.2 g / 1,2-dichloro-ethane / 1 h / 20 °C

With dihydrogen peroxide; acetic anhydride; In acetic acid;

DOI:10.1016/S0008-6215(00)00190-7

upstream raw materials:

1,6:2,5-dianhydro-4-deoxy-1-thio-D-xylo-hexitol

methyl iodide

1,6:2,5-dianhydro-4-deoxy-1-thio-D-erythro-hex-3-ulose