(S)-N₄-(benzyloxy)-N₁-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-2-isobutylsuccinamide

Base Information

• Chemical Name: (S)-N₄-(benzyloxy)-N₁-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-2-isobutylsuccinamide
• CAS No.: 927828-06-6
• Molecular Formula: C₂₂H₃₅N₃O₄
• Molecular Weight: 405.538
• Mol file: 927828-06-6.mol

Synonyms:(S)-N₄-(benzyloxy)-N₁-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-2-isobutylsuccinamide

Chemical Property of (S)-N₄-(benzyloxy)-N₁-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-2-isobutylsuccinamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (S)-N₄-(benzyloxy)-N₁-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-2-isobutylsuccinamide

There total 1 articles about (S)-N₄-(benzyloxy)-N₁-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-2-isobutylsuccinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

(S)-3-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-ylcarbamoyl)-5-methylhexanoic acid (927828-05-5) + O-benzylhydoxylamine hydrochloride (2687-43-6) → (S)-N4-(benzyloxy)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-2-isobutylsuccinamide (927828-06-6)

Guidance literature:

With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; N,N-dimethyl-formamide; at 0 - 20 ℃;

Reference yield: 98.0%

(S)-N4-(benzyloxy)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-2-isobutylsuccinamide (927828-06-6) → (S)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4-hydroxy-2-isobutylsuccinamide (927827-97-2,145337-55-9)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃;

upstream raw materials:

(S)-3-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-ylcarbamoyl)-5-methylhexanoic acid

O-benzylhydoxylamine hydrochloride

Downstream raw materials:

(S)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4-hydroxy-2-isobutylsuccinamide