2-Fluoro-6-hydroxymethyl pyridine

Base Information

Chemical Name:2-Fluoro-6-hydroxymethyl pyridine
CAS No.:315180-17-7
Molecular Formula:C6H6FNO
Molecular Weight:127.118
Hs Code.:2933399090
European Community (EC) Number:862-313-6
DSSTox Substance ID:DTXSID30476416
Wikidata:Q82307668
Mol file:315180-17-7.mol

Synonyms:315180-17-7;2-Fluoro-6-hydroxymethyl pyridine;(6-fluoropyridin-2-yl)methanol;(6-Fluoropyridin-2-yl)-methanol;6-Fluoro-2-pyridinemethanol;(6-Fluoro-2-pyridinyl)methanol;MFCD07783827;(6-Fluoro-pyridin-2-yl)-methanol;2-Pyridinemethanol, 6-fluoro-;(6-Fluoro-2-pyridyl)methanol;SCHEMBL4321081;2-fluoro-6-hydroxymethylpyridine;AMY9105;DTXSID30476416;OWTCZNAMUJIMOC-UHFFFAOYSA-N;BCP33721;AKOS006284934;CS-W006285;DS-2364;SB21156;AC-15174;SY015411;BB 0261659;EN300-1699861;A848092;J-509482

Suppliers and Price of 2-Fluoro-6-hydroxymethyl pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Fluoro-6-hydroxymethylpyridine
25mg
$ 45.00

Labseeker
2-FLUORO-6-HYDROXYMETHYLPYRIDINE 95
5g
$ 583.00

Crysdot
(6-Fluoropyridin-2-yl)-methanol 97%
25g
$ 933.00

Crysdot
(6-Fluoropyridin-2-yl)-methanol 97%
10g
$ 517.00

Crysdot
(6-Fluoropyridin-2-yl)-methanol 97%
1g
$ 115.00

Crysdot
(6-Fluoropyridin-2-yl)-methanol 97%
5g
$ 330.00

Chemenu
(6-Fluoropyridin-2-yl)-methanol 97%
5g
$ 311.00

Chemenu
(6-Fluoropyridin-2-yl)-methanol 97%
10g
$ 488.00

Chemenu
(6-Fluoropyridin-2-yl)-methanol 97%
25g
$ 880.00

Apolloscientific
(6-Fluoro-2-pyridyl)methanol 97%
5g
$ 368.00

Total 36 raw suppliers

Chemical Property of 2-Fluoro-6-hydroxymethyl pyridine

Chemical Property:

Vapor Pressure:0.071mmHg at 25°C
Refractive Index:1.524
Boiling Point:218.977 °C at 760 mmHg
PKA:13.08±0.10(Predicted)
Flash Point:86.234 °C
PSA：33.12000
Density:1.263 g/cm³
LogP:0.71300
Storage Temp.:2-8°C
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:127.043341977
Heavy Atom Count:9
Complexity:89.1

Purity/Quality:

97% ^*data from raw suppliers

2-Fluoro-6-hydroxymethylpyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC(=C1)F)CO

Technology Process of 2-Fluoro-6-hydroxymethyl pyridine

There total 5 articles about 2-Fluoro-6-hydroxymethyl pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₉H₈FNO₄

: 315180-17-7
2-fluoro-6-hydroxymethylpyridine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at -78 ℃; for 0.5h;
DOI:10.1055/s-2002-20970

Reference yield:

: 315180-16-6
6-(chloromethyl)-2-fluoropyridine

: 315180-17-7
2-fluoro-6-hydroxymethylpyridine

Guidance literature:: With potassium carbonate; In water; Heating;
DOI:10.1021/jo9804339

Reference yield:

: 407-22-7
2-fluoro-6-methylpyridine

: 315180-17-7
2-fluoro-6-hydroxymethylpyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / N-chlorosuccinimide; benzoyl peroxide; HCl / acetonitrile; acetic acid / Heating

2: potassium carbonate / H₂O / Heating

With hydrogenchloride; N-chloro-succinimide; potassium carbonate; dibenzoyl peroxide; In water; acetic acid; acetonitrile; 1: Chlorination / 2: Hydrolysis;
DOI:10.1021/jo9804339