4-((3-methoxybenzyl)(3,4,5-trimethoxyphenyl)amino)-4-oxobutanoic acid

Base Information

• Chemical Name: 4-((3-methoxybenzyl)(3,4,5-trimethoxyphenyl)amino)-4-oxobutanoic acid
• CAS No.: 1256554-13-8
• Molecular Formula: C₂₁H₂₅NO₇
• Molecular Weight: 403.432
• Mol file: 1256554-13-8.mol

Synonyms:4-((3-methoxybenzyl)(3,4,5-trimethoxyphenyl)amino)-4-oxobutanoic acid

Chemical Property of 4-((3-methoxybenzyl)(3,4,5-trimethoxyphenyl)amino)-4-oxobutanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-((3-methoxybenzyl)(3,4,5-trimethoxyphenyl)amino)-4-oxobutanoic acid

There total 4 articles about 4-((3-methoxybenzyl)(3,4,5-trimethoxyphenyl)amino)-4-oxobutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

succinic acid anhydride (108-30-5) + 3,4,5-trimethoxy-N-(3-methoxybenzyl)aniline (1175882-92-4) → 4-((3-methoxybenzyl)(3,4,5-trimethoxyphenyl)amino)-4-oxobutanoic acid (1256554-13-8)

Guidance literature:

With dmap; triethylamine; In chloroform; at 20 ℃;

Reference yield:

(3-methoxybenzylidene)-(3,4,5-trimethoxyphenyl)amine (387850-69-3) → 4-((3-methoxybenzyl)(3,4,5-trimethoxyphenyl)amino)-4-oxobutanoic acid (1256554-13-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol

2: dmap; triethylamine / chloroform / 20 °C

With dmap; sodium tetrahydroborate; triethylamine; In methanol; chloroform;

Reference yield:

3-methoxy-benzaldehyde (591-31-1) → 4-((3-methoxybenzyl)(3,4,5-trimethoxyphenyl)amino)-4-oxobutanoic acid (1256554-13-8)

Guidance literature:

Multi-step reaction with 3 steps

1: methanol / 3 h / 20 °C

2: sodium tetrahydroborate / methanol

3: dmap; triethylamine / chloroform / 20 °C

With dmap; sodium tetrahydroborate; triethylamine; In methanol; chloroform;

upstream raw materials:

succinic acid anhydride

3,4,5-trimethoxy-N-(3-methoxybenzyl)aniline

(3-methoxybenzylidene)-(3,4,5-trimethoxyphenyl)amine

3-methoxy-benzaldehyde

Downstream raw materials:

4-(3-benzyl-4,5,6,11-tetramethoxy-3H-dibenzo[b,f][1,2,3] triazolo-[4,5-d]azocin-8(9H)-yl)-4-oxobutanoic acid

4-(1-benzyl-4,5,6,11-tetramethoxy-1H-dibenzo[b,f][1,2,3]triazolo[4,5-d]azocin-8(9H)-yl)-4-oxobutanoic acid

4-(3-(4-isothiocyanatophenyl)-4,5,6,11-tetramethoxy-3H-dibenzo[b,f][1,2,3]triazolo[4,5-d]azocin-8(9H)-yl)-4-oxobutanoic acid

4-(1-(4-isothiocyanatophenyl)-4,5,6,11-tetramethoxy-1H-dibenzo[b,f][1,2,3]triazolo[4,5-d]-azocin-8(9H)-yl)-4-oxobutanoic acid