(S)-[N-3-(4-(2-(5-methyl-(1,3,4)-oxadiazol-2-yl)-pyrid in-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

Base Information

Chemical Name:(S)-[N-3-(4-(2-(5-methyl-(1,3,4)-oxadiazol-2-yl)-pyrid in-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide
CAS No.:380382-36-5
Molecular Formula:C₂₀H₁₈FN₅O₄
Molecular Weight:411.392
Hs Code.:

Synonyms:(S)-[N-3-(4-(2-(5-methyl-(1,3,4)-oxadiazol-2-yl)-pyrid in-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

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Chemical Property of (S)-[N-3-(4-(2-(5-methyl-(1,3,4)-oxadiazol-2-yl)-pyrid in-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

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Technology Process of (S)-[N-3-(4-(2-(5-methyl-(1,3,4)-oxadiazol-2-yl)-pyrid in-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

There total 3 articles about (S)-[N-3-(4-(2-(5-methyl-(1,3,4)-oxadiazol-2-yl)-pyrid in-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 380380-59-6
2-(2-methyl-[1,3,4]oxadiazol-5-yl)-5-bromopyridine

: 188975-86-2
N-({(5S)-3-[3-fluoro-4-(trimethylstannyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide

: 380382-36-5
(S)-[N-3-(4-(2-(5-methyl-(1,3,4)-oxadiazol-2-yl)-pyrid in-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

Guidance literature:: With lithium chloride; In 1-methyl-pyrrolidin-2-one; water;

Reference yield:

: 149524-45-8
(S)-N-[3-(3-fluoro-4-iodophenyl)-2-oxo-1,3-oxazolidine-5-ylmethyl]acetamide

: 380382-36-5
(S)-[N-3-(4-(2-(5-methyl-(1,3,4)-oxadiazol-2-yl)-pyrid in-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: hexamethyldistannane / 1,4-dioxane; dichlorobis(triphenylphosphine)palladium[II]

2: lithium chloride / 1-methyl-pyrrolidin-2-one; water

With hexamethyldistannane; lithium chloride; In 1,4-dioxane; 1-methyl-pyrrolidin-2-one; water; dichlorobis(triphenylphosphine)palladium[II];

Reference yield:

: 380380-60-9
2-(1,2,3,4-tetrazol-5-yl)-5-bromopyridine

: 380382-36-5
(S)-[N-3-(4-(2-(5-methyl-(1,3,4)-oxadiazol-2-yl)-pyrid in-5-yl)-3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetic anhydride

2: lithium chloride / 1-methyl-pyrrolidin-2-one; water

With lithium chloride; In 1-methyl-pyrrolidin-2-one; water; acetic anhydride;