Technology Process of Acetamide, N-(6-hydroxy-2-benzothiazolyl)- (9CI)
There total 5 articles about Acetamide, N-(6-hydroxy-2-benzothiazolyl)- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / 60 °C / Microwave irradiation
2: sodium hydroxide / N,N-dimethyl-formamide
With
N-ethyl-N,N-diisopropylamine; sodium hydroxide;
In
N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.6b01086
- Guidance literature:
-
Multi-step reaction with 3 steps
1: acetic acid; lithium bromide; bromine / 40 °C
2: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / 60 °C / Microwave irradiation
3: sodium hydroxide / N,N-dimethyl-formamide
With
bromine; acetic acid; N-ethyl-N,N-diisopropylamine; lithium bromide; sodium hydroxide;
In
N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.6b01086
- Guidance literature:
-
Multi-step reaction with 4 steps
1: trifluoroacetic acid / Isopropyl acetate / 16 h / Reflux
2: acetic acid; lithium bromide; bromine / 40 °C
3: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / 60 °C / Microwave irradiation
4: sodium hydroxide / N,N-dimethyl-formamide
With
bromine; acetic acid; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; lithium bromide; sodium hydroxide;
In
Isopropyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.6b01086
