4-Fluoro-7-methyl-1H-indole

Base Information

Chemical Name:4-Fluoro-7-methyl-1H-indole
CAS No.:313337-32-5
Molecular Formula:C₉H₈FN
Molecular Weight:149.168
Hs Code.:2933998090
DSSTox Substance ID:DTXSID90593517
Wikidata:Q82488016
Mol file:313337-32-5.mol

Synonyms:4-Fluoro-7-methyl-1H-indole;313337-32-5;4-Fluoro-7-methylindole;1H-Indole,4-fluoro-7-methyl-(9CI);MFCD09027019;SCHEMBL6870752;AMY9655;DTXSID90593517;HQIRUGMHWJZMJJ-UHFFFAOYSA-N;AKOS006290555;AC-29854;AS-49533;DA-39393;SY033206;CS-0309248;EN300-170862;I11357;A875951;W-204219;Z1198182495

Suppliers and Price of 4-Fluoro-7-methyl-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Fluoro-7-methylindole
25mg
$ 45.00

SynQuest Laboratories
4-Fluoro-7-methylindole
1 g
$ 549.00

SynQuest Laboratories
4-Fluoro-7-methylindole
250 mg
$ 224.00

Labseeker
4-fluoro-7-methyl-1H-indole 95
10g
$ 2200.00

Labseeker
4-fluoro-7-methyl-1H-indole 95
5g
$ 1417.00

Labseeker
4-fluoro-7-methyl-1H-indole 95
1g
$ 1017.00

Chemenu
4-Fluoro-7-methyl-1H-indole 95%
5g
$ 707.00

Apolloscientific
4-Fluoro-7-methylindole
5g
$ 910.00

Apolloscientific
4-Fluoro-7-methylindole
250mg
$ 140.00

Apolloscientific
4-Fluoro-7-methylindole
1g
$ 343.00

Total 16 raw suppliers

Chemical Property of 4-Fluoro-7-methyl-1H-indole

Chemical Property:

Boiling Point:265.8±20.0 °C(Predicted)
PKA:16.70±0.30(Predicted)
PSA：15.79000
Density:1.219±0.06 g/cm3(Predicted)
LogP:2.61540
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:149.064077422
Heavy Atom Count:11
Complexity:149

Purity/Quality:

97% ^*data from raw suppliers

4-Fluoro-7-methylindole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=C(C=C1)F)C=CN2

Technology Process of 4-Fluoro-7-methyl-1H-indole

There total 2 articles about 4-Fluoro-7-methyl-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 313337-35-8
methyl 4-fluoro-1H-indole-7-carboxylate

: 313337-32-5
4-fluoro-7-methyl-1H-indole

Guidance literature:

Reference yield:

: 313337-32-5
4-fluoro-7-methyl-1H-indole

Guidance literature:

Reference yield:

: 313337-32-5
4-fluoro-7-methyl-1H-indole

: 1268053-43-5
2,2,2-trifluoro-N-(4-fluoro-3-{1-[4-fluoro-7-methyl-1-(2-trifluoromethoxyethyl)-1H-indole-3-carbonyl]piperidin-4-yl}benzyl)acetamide

Guidance literature:: Multi-step reaction with 6 steps

1.1: N,N-dimethyl-formamide / 0.5 h / 20 °C

2.1: sodium hydroxide / water; methanol / 0.75 h / 140 °C

2.2: pH 4

3.1: hydrogenchloride / 20 °C

4.1: sodium hydride / tetrahydrofuran; mineral oil / 0.08 h / 20 °C

4.2: 0.5 h / 20 °C

5.1: sodium hydroxide / water; methanol / 4 h / 40 °C

5.2: pH 2

6.1: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

With hydrogenchloride; sodium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; mineral oil;