methyl 3-O-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside

Base Information

• Chemical Name: methyl 3-O-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside
• CAS No.: 815589-34-5
• Molecular Formula: C₅₅H₄₈O₁₇
• Molecular Weight: 980.976
• Mol file: 815589-34-5.mol

Synonyms:methyl 3-O-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside

Chemical Property of methyl 3-O-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3-O-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside

There total 3 articles about methyl 3-O-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

methyl 3-O-(6-O-acetyl-2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside (815589-33-4) → methyl 3-O-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside (815589-34-5)

Guidance literature:

With methanol; acetyl chloride; In 1,2-dichloro-ethane; at 20 ℃;

DOI:10.1016/j.bmc.2004.09.005

Reference yield:

methyl 2,4,6-tri-O-benzoyl-α-D-mannopyranoside (125226-68-8) → methyl 3-O-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside (815589-34-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 79 percent / molecular sieves 3 Angstroem; TMSOTf / 1,2-dichloro-ethane / 0.17 h / 0 °C

2: 82 percent / acetyl chloride; MeOH / 1,2-dichloro-ethane / 20 °C

With methanol; trimethylsilyl trifluoromethanesulfonate; 3 A molecular sieve; acetyl chloride; In 1,2-dichloro-ethane;

DOI:10.1016/j.bmc.2004.09.005

Reference yield:

6-O-acetyl-2,3,4-tri-O-benzoyl-α-D-mannopyranosyl trichloroacetimidate (346441-49-4) → methyl 3-O-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside (815589-34-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 79 percent / molecular sieves 3 Angstroem; TMSOTf / 1,2-dichloro-ethane / 0.17 h / 0 °C

2: 82 percent / acetyl chloride; MeOH / 1,2-dichloro-ethane / 20 °C

With methanol; trimethylsilyl trifluoromethanesulfonate; 3 A molecular sieve; acetyl chloride; In 1,2-dichloro-ethane;

DOI:10.1016/j.bmc.2004.09.005

upstream raw materials:

methyl 3-O-(6-O-acetyl-2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside

methyl 2,4,6-tri-O-benzoyl-α-D-mannopyranoside

6-O-acetyl-2,3,4-tri-O-benzoyl-α-D-mannopyranosyl trichloroacetimidate

Downstream raw materials:

methyl 3-O-(2,3,4-tri-O-benzoyl-6-O-diphenylphosphoryl-α-D-mannopyranosyl)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside