N-(4-chlorophenyl)-N-benzyl benzophenone hydrazone

Base Information

• Chemical Name: N-(4-chlorophenyl)-N-benzyl benzophenone hydrazone
• CAS No.: 240482-76-2
• Molecular Formula: C₂₆H₂₁ClN₂
• Molecular Weight: 396.919
• Mol file: 240482-76-2.mol

Synonyms:N-(4-chlorophenyl)-N-benzyl benzophenone hydrazone

Chemical Property of N-(4-chlorophenyl)-N-benzyl benzophenone hydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of N-(4-chlorophenyl)-N-benzyl benzophenone hydrazone

There total 2 articles about N-(4-chlorophenyl)-N-benzyl benzophenone hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-benzhydrylidene-N'-(4-chlorophenyl)-hydrazine (40594-87-4) + benzyl bromide (100-39-0) → N-(4-chlorophenyl)-N-benzyl benzophenone hydrazone (240482-76-2)

Guidance literature:

N-benzhydrylidene-N'-(4-chlorophenyl)-hydrazine; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at 20 ℃; for 0.5h;

benzyl bromide; With N,N,N,N,-tetramethylethylenediamine;

DOI:10.1021/ja992077x

Reference yield:

benzophenone hydrazone (5350-57-2) → N-(4-chlorophenyl)-N-benzyl benzophenone hydrazone (240482-76-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 98 percent / Pd(OAc)2; Xantphos; t-BuONa / toluene / 1.5 h / 80 °C

2.1: LDA / tetrahydrofuran; hexane / 0.5 h / 20 °C

2.2: TMEDA

With palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium t-butanolate; lithium diisopropyl amide; In tetrahydrofuran; hexane; toluene; 1.1: Arylation / 2.1: Alkylation / 2.2: Condensation;

DOI:10.1021/ja992077x

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + N-(4-chlorophenyl)-N-benzyl benzophenone hydrazone (240482-76-2) → 6-chloro-N-benzyl-1,2,3,4-tetrahydrocarbazole (102173-26-2)

Guidance literature:

With toluene-4-sulfonic acid; In ethanol; Heating;

DOI:10.1021/ja992077x

upstream raw materials:

N-benzhydrylidene-N'-(4-chlorophenyl)-hydrazine

benzyl bromide

benzophenone hydrazone

Downstream raw materials:

6-chloro-N-benzyl-1,2,3,4-tetrahydrocarbazole