bortezomib pinacol ester

Base Information

Chemical Name:bortezomib pinacol ester
CAS No.:1029701-48-1
Molecular Formula:C₂₅H₃₅BN₄O₄
Molecular Weight:466.388
Hs Code.:

Synonyms:bortezomib pinacol ester

Suppliers and Price of bortezomib pinacol ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of bortezomib pinacol ester

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of bortezomib pinacol ester

There total 12 articles about bortezomib pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: (R)-3-methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-1-amine hydrochloride

: 114457-94-2,1608986-16-8
(S)-3-phenyl-2[(pyrazine-2-carbonyl)-amino]propionic acid

: 1029701-48-1
bortezomib pinacol ester

Guidance literature:: With 2-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)-1,1,3,3-tetramethylisouronium hexafluorophosphate; triethylamine; In dichloromethane; ethyl acetate; at 0 - 20 ℃; for 12h; Large scale;

Reference yield: 86.0%

: C₁₁H₂₄BNO₂*C₂HF₃O₂

: 114457-94-2,1608986-16-8
(S)-3-phenyl-2[(pyrazine-2-carbonyl)-amino]propionic acid

: 1029701-48-1
bortezomib pinacol ester

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; toluene; at 0 - 80 ℃; for 8h; Large scale;

Reference yield:

: 98-97-5
2-pyrazylcarboxylic acid

: 1029701-41-4
(CH₃)2CHCH₂CH(BO₂C₂(CH₃)4)NHCOCH(CH₂C₆H₅)NH₃⁽¹⁺⁾*Cl^(1-)=(CH₃)2CHCH₂CH(BO₂C₂(CH₃)4)NHCOCH(CH₂C₆H₅)NH₃Cl

: 1029701-48-1
bortezomib pinacol ester

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1021/ja800829y