4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol

Base Information

Chemical Name:4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol
CAS No.:312636-16-1
Molecular Formula:C₁₅H₁₁ClN₂OS
Molecular Weight:302.784
Hs Code.:
DSSTox Substance ID:DTXSID90353799
Nikkaji Number:J2.235.533C
Wikidata:Q27088850
Pharos Ligand ID:7CP1CY3M7CYD
ChEMBL ID:CHEMBL1076555
Mol file:312636-16-1.mol

Synonyms:4-((4-(4-chlorophenyl)-2-thiazolyl)amino)phenol;SK I-II compound

Suppliers and Price of 4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
SKI-II, Sphingosine Kinase Inhibitor
5mg
$ 366.00

TRC
SKI II
200mg
$ 770.00

TRC
SKI II
10mg
$ 55.00

Sigma-Aldrich
SKI II ≥98% (HPLC), solid
10mg
$ 169.00

Sigma-Aldrich
SKI II ≥98% (HPLC), solid
50mg
$ 645.00

Medical Isotopes, Inc.
SKI II
200 mg
$ 1275.00

DC Chemicals
SphK-I2 >98%
1 g
$ 1500.00

DC Chemicals
SphK-I2 >98%
250 mg
$ 750.00

Crysdot
SKI II 98+%
250mg
$ 750.00

Crysdot
SKI II 98+%
100mg
$ 420.00

Total 21 raw suppliers

Chemical Property of 4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol

Chemical Property:

Vapor Pressure:6.65E-11mmHg at 25°C
Refractive Index:1.709
Boiling Point:507.1°Cat760mmHg
PKA:10.17±0.26(Predicted)
Flash Point:260.5°C
PSA：73.39000
Density:1.415g/cm³
LogP:4.98570
Storage Temp.:2-8°C
Sensitive.:Air & Light Sensitive
Solubility.:DMSO: ≥20 mg/mL
XLogP3:4.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:302.0280618
Heavy Atom Count:20
Complexity:304

Purity/Quality:

99%, ^*data from raw suppliers

SKI-II, Sphingosine Kinase Inhibitor ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CSC(=N2)NC3=CC=C(C=C3)O)Cl
Uses SKI II is a nonlipid inhibitor of sphingosine kinase. SKI II s orally bioavailable and has shown significant inhibition of tumor growth in mice.

Technology Process of 4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol

There total 2 articles about 4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: