2,3,3',4,4'-penta-O-benzyl-1'-O-benzyloxymethyl-6-O-t-butyldiphenylsilylsucrose

Base Information

• Chemical Name: 2,3,3',4,4'-penta-O-benzyl-1'-O-benzyloxymethyl-6-O-t-butyldiphenylsilylsucrose
• CAS No.: 228549-30-2
• Molecular Formula: C₇₁H₇₈O₁₂Si
• Molecular Weight: 1151.48
• Mol file: 228549-30-2.mol

Synonyms:2,3,3',4,4'-penta-O-benzyl-1'-O-benzyloxymethyl-6-O-t-butyldiphenylsilylsucrose

Chemical Property of 2,3,3',4,4'-penta-O-benzyl-1'-O-benzyloxymethyl-6-O-t-butyldiphenylsilylsucrose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,3',4,4'-penta-O-benzyl-1'-O-benzyloxymethyl-6-O-t-butyldiphenylsilylsucrose

There total 1 articles about 2,3,3',4,4'-penta-O-benzyl-1'-O-benzyloxymethyl-6-O-t-butyldiphenylsilylsucrose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

2,3,3',4,4'-penta-O-benzyl-1'-O-benzyloxymethyl-6,6'-di-O-t-butyldiphenylsilylsucrose (297747-73-0) → 2,3,3',4,4'-penta-O-benzyl-1'-O-benzyloxymethylsucrose (228549-26-6) + 2,3,3',4,4'-penta-O-benzyl-1'-O-benzyloxymethyl-6-O-t-butyldiphenylsilylsucrose (228549-30-2)

Guidance literature:

With pyridine hydrogenfluoride; In methanol; diethyl ether; at 20 ℃; for 10h;

DOI:10.1080/07328300008544111

Reference yield:

2,3,3',4,4'-penta-O-benzyl-1'-O-benzyloxymethyl-6-O-t-butyldiphenylsilylsucrose (228549-30-2) → (2S,3R,4S,5S)-3,4-Bis-benzyloxy-5-benzyloxymethoxymethyl-5-[(2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-furan-2-carbaldehyde (389885-52-3)

Guidance literature:

With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -78 - 20 ℃;

DOI:10.1080/07328300008544111

Reference yield:

methanesulfonyl chloride (124-63-0) + 2,3,3',4,4'-penta-O-benzyl-1'-O-benzyloxymethyl-6-O-t-butyldiphenylsilylsucrose (228549-30-2) → 2,3,4,3',4'-penta-O-benzyl-1'-O-benzyloxymethyl-6-O-t-butyldiphenylsilyl-6'-O-mesylsucrose

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃; for 18h;

upstream raw materials:

2,3,3',4,4'-penta-O-benzyl-1'-O-benzyloxymethyl-6,6'-di-O-t-butyldiphenylsilylsucrose

Downstream raw materials:

(2S,3R,4S,5S)-3,4-Bis-benzyloxy-5-benzyloxymethoxymethyl-5-[(2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-furan-2-carbaldehyde

methyl (2,3,4-tri-O-benzyl-6-O-t-butyldiphenylsilyl-α-D-glucopyranosyl)-(1<->7)-[(E)-5,6-di-O-benzyl-2,3-dideoxy-8-O-benzyloxymethyl-β-D-lyxo-oct-2-eno-7-ulofuranosid]onate