P-METHOXYBENZYL TRITYL ETHER 97

Base Information

• Chemical Name: P-METHOXYBENZYL TRITYL ETHER 97
• CAS No.: 312493-51-9
• Molecular Formula: C27H24 O2
• Molecular Weight: 380.486
• Mol file: 312493-51-9.mol

Synonyms:p-Methoxybenzyltrityl ether

Chemical Property of P-METHOXYBENZYL TRITYL ETHER 97

Chemical Property:

• Melting Point: 132-136 °C(lit.)
• PSA: 18.46000
• LogP: 6.20390

Purity/Quality:

95% ^*data from raw suppliers

p-Methoxybenzyl trityl ether Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of P-METHOXYBENZYL TRITYL ETHER 97

There total 4 articles about P-METHOXYBENZYL TRITYL ETHER 97 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

trityl chloride (76-83-5) + 4-Methoxybenzyl alcohol (105-13-5) → (((4-methoxybenzyl)oxy)methanetriyl)tribenzene (312493-51-9)

Guidance literature:

With dmap; 4 A molecular sieve; triethylamine; In dichloromethane; at 20 ℃; for 8h;

Reference yield: 90.0%

triphenylmethyl alcohol (76-84-6) + 4-Methoxybenzyl alcohol (105-13-5) → (((4-methoxybenzyl)oxy)methanetriyl)tribenzene (312493-51-9)

Guidance literature:

With iron(III) chloride hexahydrate; at 45 ℃; for 1h; Reagent/catalyst; Temperature; Microwave irradiation;

DOI:10.1016/j.tet.2015.07.040

Reference yield: 65.0%

cyclohexane-1,2-epoxide (286-20-4) + trityl chloride (76-83-5) + 4-Methoxybenzyl alcohol (105-13-5) → (((4-methoxybenzyl)oxy)methanetriyl)tribenzene (312493-51-9) + (1S,2S)-2-(4-Methoxy-benzyloxy)-cyclohexanol

Guidance literature:

cyclohexane-1,2-epoxide; 4-Methoxybenzyl alcohol; With copper(II) bis(tetrafluoroborate); In dichloromethane; at 20 ℃; for 24h; Inert atmosphere;

trityl chloride; With pyridine; at 70 ℃; for 16h;

DOI:10.1016/j.tetlet.2011.10.090

upstream raw materials:

trityl chloride

4-Methoxybenzyl alcohol

cyclohexane-1,2-epoxide

triphenylmethyl alcohol

Downstream raw materials:

(3aR,6R,6aR)-4-Methoxy-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxole

4-[(triphenylmethyl)oxy]butanol

6-(triphenylmethyloxy)-1-hexanol

(1S,2R,4S)-1-isopropyl-4-methyl-2-trityloxy-cyclohexane