(Z)-ethyl 3-(4-chlorophenyl)-2-(methylthiocarbonylamino)acrylate

Base Information

• Chemical Name: (Z)-ethyl 3-(4-chlorophenyl)-2-(methylthiocarbonylamino)acrylate
• CAS No.: 126415-83-6
• Molecular Formula: C₁₃H₁₄ClNO₃S
• Molecular Weight: 299.778
• Mol file: 126415-83-6.mol

Synonyms:(Z)-ethyl 3-(4-chlorophenyl)-2-(methylthiocarbonylamino)acrylate

Chemical Property of (Z)-ethyl 3-(4-chlorophenyl)-2-(methylthiocarbonylamino)acrylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (Z)-ethyl 3-(4-chlorophenyl)-2-(methylthiocarbonylamino)acrylate

There total 1 articles about (Z)-ethyl 3-(4-chlorophenyl)-2-(methylthiocarbonylamino)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl N-(ethoxycarbonylmethyl)iminodithiocarbonate (54985-61-4) + 4-chlorobenzaldehyde (104-88-1) → (Z)-ethyl 3-(4-chlorophenyl)-2-(methylthiocarbonylamino)acrylate (126415-83-6)

Guidance literature:

Yield given. Multistep reaction;

Reference yield: 100.0%

(Z)-ethyl 3-(4-chlorophenyl)-2-(methylthiocarbonylamino)acrylate (126415-83-6) → (Z)-2-(p-Chlorophenyl)-1-(ethoxycarbonyl)vinyl isocyanate

Guidance literature:

With chloro-trimethyl-silane; triethylamine; In toluene; for 2h; Heating;

DOI:10.1021/jo00088a064

Reference yield:

(Z)-ethyl 3-(4-chlorophenyl)-2-(methylthiocarbonylamino)acrylate (126415-83-6) → 1,3-Bis<(Z)-2-(p-chlorophenyl)-1-(ethoxycarbonyl)vinyl>urea

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / Et₃N, Me₃SiCl / toluene / 2 h / Heating

2: 100 percent / ethyl acetate / 0.25 h / Heating

With chloro-trimethyl-silane; ethyl acetate; triethylamine; In toluene;

DOI:10.1021/jo00088a064

upstream raw materials:

dimethyl N-(ethoxycarbonylmethyl)iminodithiocarbonate

4-chlorobenzaldehyde