2-(2-hydroxymethyl-5-methoxyphenyl)-3-(3-methoxyphenyl)-N-methylpropylamine

Base Information

Chemical Name:2-(2-hydroxymethyl-5-methoxyphenyl)-3-(3-methoxyphenyl)-N-methylpropylamine
CAS No.:98748-63-1
Molecular Formula:C₁₉H₂₅NO₃
Molecular Weight:315.412
Hs Code.:

Synonyms:2-(2-hydroxymethyl-5-methoxyphenyl)-3-(3-methoxyphenyl)-N-methylpropylamine

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Chemical Property of 2-(2-hydroxymethyl-5-methoxyphenyl)-3-(3-methoxyphenyl)-N-methylpropylamine

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Technology Process of 2-(2-hydroxymethyl-5-methoxyphenyl)-3-(3-methoxyphenyl)-N-methylpropylamine

There total 5 articles about 2-(2-hydroxymethyl-5-methoxyphenyl)-3-(3-methoxyphenyl)-N-methylpropylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 98748-62-0
2-(2-hydroxymethyl-5-methoxyphenyl)-3-(3-methoxyphenyl)-N-methylpropionamide

: 98748-63-1
2-(2-hydroxymethyl-5-methoxyphenyl)-3-(3-methoxyphenyl)-N-methylpropylamine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 11h; Heating;

Reference yield:

: 43088-72-8
6-Methoxyisochroman-3-one

: 98748-63-1
2-(2-hydroxymethyl-5-methoxyphenyl)-3-(3-methoxyphenyl)-N-methylpropylamine

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / piperidine / 2 h / 140 °C

2: 92 percent / hydrogen / Pd-C / ethyl acetate / 10 h

3: 71 percent / ethanol / 5 h / Heating

4: 93 percent / lithium aluminium hydride / tetrahydrofuran / 11 h / Heating

With piperidine; lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; ethyl acetate;

Reference yield:

: 98748-58-4
6-methoxy-4-(3-methoxybenzylidene)-isochroman-3-one

: 98748-63-1
2-(2-hydroxymethyl-5-methoxyphenyl)-3-(3-methoxyphenyl)-N-methylpropylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / hydrogen / Pd-C / ethyl acetate / 10 h

2: 71 percent / ethanol / 5 h / Heating

3: 93 percent / lithium aluminium hydride / tetrahydrofuran / 11 h / Heating

With lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol; ethyl acetate;