2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)imidazolyl]-1-deoxy-D-gluco-hept-2-enitol

Base Information

Chemical Name:2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)imidazolyl]-1-deoxy-D-gluco-hept-2-enitol
CAS No.:191097-85-5
Molecular Formula:C₄₆H₄₆N₂O₆
Molecular Weight:722.881
Hs Code.:

Synonyms:2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)imidazolyl]-1-deoxy-D-gluco-hept-2-enitol

Suppliers and Price of 2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)imidazolyl]-1-deoxy-D-gluco-hept-2-enitol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)imidazolyl]-1-deoxy-D-gluco-hept-2-enitol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)imidazolyl]-1-deoxy-D-gluco-hept-2-enitol

There total 4 articles about 2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)imidazolyl]-1-deoxy-D-gluco-hept-2-enitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 191097-84-4
acetyl-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)imidazolyl]-1-deoxy-α-D-gluco-2-heptulopyranoside

: 191097-85-5
2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)imidazolyl]-1-deoxy-D-gluco-hept-2-enitol

Guidance literature:: With trimethylsilyl trifluoromethanesulfonate; In acetonitrile; at 60 ℃; for 20h;
DOI:10.1080/07328309708006530

Reference yield:

: 615-15-6
2-Methyl-1H-benzimidazole

: 191097-85-5
2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)imidazolyl]-1-deoxy-D-gluco-hept-2-enitol

Guidance literature:: Multi-step reaction with 4 steps

1.1: 64 percent / acetonitrile / 3 h / Heating

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -80 °C

2.2: 81 percent / tetrahydrofuran; hexane / 0.5 h / -80 °C

3.1: 86 percent / sodium hydride / dimethylformamide / 0.25 h / 20 °C

4.1: 70 percent / trimethylsilyl trifluoromethanesulfonate / acetonitrile / 20 h / 60 °C

With n-butyllithium; trimethylsilyl trifluoromethanesulfonate; sodium hydride; In tetrahydrofuran; hexane; N,N-dimethyl-formamide; acetonitrile; 1.1: Alkylation / 2.1: Metallation / 2.2: Addition / 3.1: Acetylation / 4.1: Elimination;
DOI:10.1080/07328309708006530

Reference yield:

: 117740-07-5
1-benzyloxymethyl-2-methylimidazole

: 191097-85-5
2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)imidazolyl]-1-deoxy-D-gluco-hept-2-enitol

Guidance literature:: Multi-step reaction with 3 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -80 °C

1.2: 81 percent / tetrahydrofuran; hexane / 0.5 h / -80 °C

2.1: 86 percent / sodium hydride / dimethylformamide / 0.25 h / 20 °C

3.1: 70 percent / trimethylsilyl trifluoromethanesulfonate / acetonitrile / 20 h / 60 °C

With n-butyllithium; trimethylsilyl trifluoromethanesulfonate; sodium hydride; In tetrahydrofuran; hexane; N,N-dimethyl-formamide; acetonitrile; 1.1: Metallation / 1.2: Addition / 2.1: Acetylation / 3.1: Elimination;
DOI:10.1080/07328309708006530