C₄₉H₇₀N₆O₁₂Si

Base Information Edit

Chemical Name:C₄₉H₇₀N₆O₁₂Si
CAS No.:1095089-47-6
Molecular Formula:C₄₉H₇₀N₆O₁₂Si
Molecular Weight:963.213
Hs Code.:
Mol file:1095089-47-6.mol

C<sub>49</sub>H<sub>70</sub>N<sub>6</sub>O<sub>12</sub>Si

Synonyms:C₄₉H₇₀N₆O₁₂Si

Suppliers and Price of C₄₉H₇₀N₆O₁₂Si

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₄₉H₇₀N₆O₁₂Si Edit

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₄₉H₇₀N₆O₁₂Si

There total 14 articles about C₄₉H₇₀N₆O₁₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 1095089-45-4
(2S,4R)-tert-butyl 2-amino-5-azido-4-(tertbutyldimethylsilyloxy)pentanoate

: 1095089-39-6
(2S,2’’’S)-2-(benzyloxcarbonylamino)-3-(4’,4’’-bis-methoxy-3’’-[tert-butyloxycarbonylamino-2’’’-methoxycarbonylethyl]-biphenyl-3’-yl)-propionic acid

: 1095089-47-6
C₄₉H₇₀N₆O₁₂Si

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; for 16h; Inert atmosphere;
DOI:10.1039/b811583d

Reference yield:

: 1095089-33-0
(S)-2-amino-3-(5'-iodo-2'-methoxyphenyl)propanoic acid hydrochloride

: 1095089-47-6
C₄₉H₇₀N₆O₁₂Si

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydrogencarbonate / 1,4-dioxane; water / 16.17 h / 0 - 20 °C / Inert atmosphere

2: caesium carbonate; palladium diacetate; tris-(o-tolyl)phosphine / 1,4-dioxane; water / 8 h / 80 °C / Inert atmosphere

3: benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere

With palladium diacetate; sodium hydrogencarbonate; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; tris-(o-tolyl)phosphine; In 1,4-dioxane; dichloromethane; water; 2: |Suzuki Coupling;
DOI:10.1002/asia.201000908

Reference yield:

: 1095089-43-2
(2S,4R)-N-(tert-butoxycarbonyl)-4-(tert-butyldimethylsilyloxy)-5-oxopyrrolidine-2-carboxylic acid tert-butyl ester

: 1095089-47-6
C₄₉H₇₀N₆O₁₂Si

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium tetrahydroborate / water; ethanol / 22 h / 0 - 20 °C / pH 7 / Inert atmosphere

2.1: triphenylphosphine; hydrogen azide; di-isopropyl azodicarboxylate / toluene / 4 h / Inert atmosphere

3.1: 2,6-dimethylpyridine; t-butyldimethylsiyl triflate / dichloromethane / 0.25 h / 20 °C / Inert atmosphere

3.2: 1 h / Inert atmosphere

4.1: benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere

With 2,6-dimethylpyridine; sodium tetrahydroborate; hydrogen azide; di-isopropyl azodicarboxylate; t-butyldimethylsiyl triflate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In ethanol; dichloromethane; water; toluene; 2.1: |Mitsunobu Displacement;
DOI:10.1002/asia.201000908