Methyl 2-{[8-Fluoro-3-(Bromomethyl)-2-phenylquinolin-4-yl]carbonyl}-1-phenylhydrazinecarboxylate

Base Information

Chemical Name:Methyl 2-{[8-Fluoro-3-(Bromomethyl)-2-phenylquinolin-4-yl]carbonyl}-1-phenylhydrazinecarboxylate
CAS No.:914654-44-7
Molecular Formula:C₂₅H₁₉BrFN₃O₃
Molecular Weight:508.347
Hs Code.:

Synonyms:Methyl 2-{[8-Fluoro-3-(Bromomethyl)-2-phenylquinolin-4-yl]carbonyl}-1-phenylhydrazinecarboxylate

Suppliers and Price of Methyl 2-{[8-Fluoro-3-(Bromomethyl)-2-phenylquinolin-4-yl]carbonyl}-1-phenylhydrazinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl 2-{[8-Fluoro-3-(Bromomethyl)-2-phenylquinolin-4-yl]carbonyl}-1-phenylhydrazinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methyl 2-{[8-Fluoro-3-(Bromomethyl)-2-phenylquinolin-4-yl]carbonyl}-1-phenylhydrazinecarboxylate

There total 4 articles about Methyl 2-{[8-Fluoro-3-(Bromomethyl)-2-phenylquinolin-4-yl]carbonyl}-1-phenylhydrazinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 914654-43-6
2-(1,1-dimethylethyl) 1-methyl 2-{[8-fluoro-3-(bromomethyl)-2-phenylquinolin-4-yl]carbonyl}-1-phenylhydrazinedicarboxylate

: 914654-44-7
Methyl 2-{[8-Fluoro-3-(Bromomethyl)-2-phenylquinolin-4-yl]carbonyl}-1-phenylhydrazinecarboxylate

Guidance literature:: With trifluoroacetic acid; In dichloromethane;
DOI:10.1016/j.bmcl.2006.08.085

Reference yield:

: 914654-41-4
methyl 2-[(8-fluoro-3-methyl-2-phenylquinolin-4-yl)carbonyl]-1-phenylhydrazinecarboxylate

: 914654-44-7
Methyl 2-{[8-Fluoro-3-(Bromomethyl)-2-phenylquinolin-4-yl]carbonyl}-1-phenylhydrazinecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: NaH / tetrahydrofuran

2: NBS / CCl₄ / Irradiation

3: TFA / CH₂Cl₂

With N-Bromosuccinimide; sodium hydride; trifluoroacetic acid; In tetrahydrofuran; tetrachloromethane; dichloromethane;
DOI:10.1016/j.bmcl.2006.08.085

Reference yield:

: 914654-42-5
2-(1,1-dimethylethyl) 1-methyl 2-[(8-fluoro-3-methyl-2-phenylquinolin-4-yl)carbonyl]-1-phenylhydrazinedicarboxylate

: 914654-44-7
Methyl 2-{[8-Fluoro-3-(Bromomethyl)-2-phenylquinolin-4-yl]carbonyl}-1-phenylhydrazinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: NBS / CCl₄ / Irradiation

2: TFA / CH₂Cl₂

With N-Bromosuccinimide; trifluoroacetic acid; In tetrachloromethane; dichloromethane;
DOI:10.1016/j.bmcl.2006.08.085