Technology Process of C14H18O4
There total 2 articles about C14H18O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Diethyl methylmalonate;
With
sodium ethanolate;
In
ethanol;
for 0.25h;
Inert atmosphere;
Schlenk technique;
Glovebox;
4-isopropylbenzyl chloride;
In
ethanol;
for 3h;
Inert atmosphere;
Schlenk technique;
Glovebox;
Reflux;
With
potassium hydroxide;
In
ethanol; water;
for 4h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium tetrahydroborate / tetrahydrofuran; methanol / 0 - 20 °C / Inert atmosphere; Schlenk technique; Glovebox
1.2: 5 - 20 °C / Inert atmosphere; Schlenk technique; Glovebox
2.1: sodium ethanolate / ethanol / 0.25 h / Inert atmosphere; Schlenk technique; Glovebox
2.2: 3 h / Inert atmosphere; Schlenk technique; Glovebox; Reflux
2.3: 4 h / Reflux
With
sodium tetrahydroborate; sodium ethanolate;
In
tetrahydrofuran; methanol; ethanol;
- Guidance literature:
-
at 180 ℃;
Inert atmosphere;
Schlenk technique;
Glovebox;