3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-5-yl 4-nitrobenzoate

Base Information

• Chemical Name: 3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-5-yl 4-nitrobenzoate
• CAS No.: 93818-38-3
• Molecular Formula: C₁₇H₁₇NO₄
• Molecular Weight: 299.326
• Mol file: 93818-38-3.mol

Synonyms:(1RS,2RS,6RS,7RS,8SR)-tricyclo[5.2.1.0^2,6]dec-4-en-8-yl 4-nitrobenzoate

Chemical Property of 3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-5-yl 4-nitrobenzoate

Chemical Property:

• Vapor Pressure: 2.38E-08mmHg at 25°C

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-5-yl 4-nitrobenzoate

There total 2 articles about 3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-5-yl 4-nitrobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

endo-Dicyclopentadien (1755-01-7,25038-78-2) + 4-nitro-benzoyl chloride (122-04-3) → (1RS,2RS,6RS,7RS,8SR)-tricyclo[5.2.1.02,6]dec-4-en-8-yl 4-nitrobenzoate (93818-38-3) + (1RS,2SR,6RS,7RS,8SR)-tricyclo[5.2.1.02,6]dec-3-en-8-yl 4-nitrobenzoate

Guidance literature:

endo-Dicyclopentadien; With sulfuric acid; water; for 5h; Heating;

4-nitro-benzoyl chloride; With pyridine; at 0 - 20 ℃;

DOI:10.1002/hlca.200490151

Reference yield:

→ (1RS,2RS,6RS,7RS,8SR)-tricyclo[5.2.1.02,6]dec-4-en-8-yl 4-nitrobenzoate (93818-38-3)

Guidance literature:

DOI:10.1177/0739986302024003001

Reference yield: 96.0%

(1RS,2RS,6RS,7RS,8SR)-tricyclo[5.2.1.02,6]dec-4-en-8-yl 4-nitrobenzoate (93818-38-3) → (1RS,2RS,6RS,7RS,8SR)-tricyclo[5.2.1.02,6]dec-4-en-8-ol (133-21-1,36807-74-6,42913-38-2,51175-97-4,54418-52-9)

Guidance literature:

With sodium hydroxide; In methanol; water; for 2h; Heating;

DOI:10.1002/hlca.200490151

upstream raw materials:

endo-Dicyclopentadien

4-nitro-benzoyl chloride

Downstream raw materials:

(1RS,2RS,6RS,7RS,8SR)-tricyclo[5.2.1.0^2,6]dec-4-en-8-ol

(1RS,2RS,6RS,7RS,8SR)-tricyclo[5.2.1.0^2,6]dec-4-en-8-yl acetate

(1R,2R,6R,7R,8S)-tricyclo[5.2.1.0^2,6]dec-4-en-8-ol

(1S,2S,6S,7S,8R)-tricyclo[5.2.1.0^2,6]dec-4-en-8-ol

Refernces