6β-<2-acetamido>-17-(cyclopropylmethyl)4,5α-epoxy-3,14-dihydroxymorphinan

Base Information

Chemical Name:6β-<2-acetamido>-17-(cyclopropylmethyl)4,5α-epoxy-3,14-dihydroxymorphinan
CAS No.:103500-49-8
Molecular Formula:C₃₀H₃₅N₃O₆
Molecular Weight:533.624
Hs Code.:

6β-<2-<N-(benzyloxycarbonyl)amino>acetamido>-17-(cyclopropylmethyl)4,5α-epoxy-3,14-dihydroxymorphinan

Synonyms:6β-<2-acetamido>-17-(cyclopropylmethyl)4,5α-epoxy-3,14-dihydroxymorphinan

Suppliers and Price of 6β-<2-acetamido>-17-(cyclopropylmethyl)4,5α-epoxy-3,14-dihydroxymorphinan

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6β-<2-acetamido>-17-(cyclopropylmethyl)4,5α-epoxy-3,14-dihydroxymorphinan

Chemical Property:

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Technology Process of 6β-<2-acetamido>-17-(cyclopropylmethyl)4,5α-epoxy-3,14-dihydroxymorphinan

There total 2 articles about 6β-<2-acetamido>-17-(cyclopropylmethyl)4,5α-epoxy-3,14-dihydroxymorphinan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 63463-07-0
beta-Naltrexamine dihydrochloride

: 41445-61-8
C₁₅H₁₉NO₆

: 103500-49-8
6β-<2-acetamido>-17-(cyclopropylmethyl)4,5α-epoxy-3,14-dihydroxymorphinan

Guidance literature:: With 4-methyl-morpholine; In tetrahydrofuran; water; N,N-dimethyl-formamide; at -30 - 20 ℃; for 2.75h; Yield given;
DOI:10.1021/jm00160a011

Reference yield:

: 1138-80-3
N-(Benzyloxycarbonyl)glycine

: 103500-49-8
6β-<2-acetamido>-17-(cyclopropylmethyl)4,5α-epoxy-3,14-dihydroxymorphinan

Guidance literature:: Multi-step reaction with 2 steps

1: N-methylmorpholine / tetrahydrofuran

2: N-methylmorpholine / dimethylformamide; tetrahydrofuran; H₂O / 2.75 h / -30 - 20 °C

With 4-methyl-morpholine; In tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00160a011