(R,Z)-N-tert-butyl-4-(3,4-dichlorophenyl)-2-hydrazono-4-phenyl butanamide

Base Information

Chemical Name:(R,Z)-N-tert-butyl-4-(3,4-dichlorophenyl)-2-hydrazono-4-phenyl butanamide
CAS No.:1637758-80-5
Molecular Formula:C₂₀H₂₃Cl₂N₃O
Molecular Weight:392.328
Hs Code.:

Synonyms:(R,Z)-N-tert-butyl-4-(3,4-dichlorophenyl)-2-hydrazono-4-phenyl butanamide

Suppliers and Price of (R,Z)-N-tert-butyl-4-(3,4-dichlorophenyl)-2-hydrazono-4-phenyl butanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R,Z)-N-tert-butyl-4-(3,4-dichlorophenyl)-2-hydrazono-4-phenyl butanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R,Z)-N-tert-butyl-4-(3,4-dichlorophenyl)-2-hydrazono-4-phenyl butanamide

There total 4 articles about (R,Z)-N-tert-butyl-4-(3,4-dichlorophenyl)-2-hydrazono-4-phenyl butanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1637758-69-0
(R)-N-tert-butyl-4-(3,4-dichlorophenyl)-2-oxo-4-phenylbutanamide

: 1637758-80-5
(R,Z)-N-tert-butyl-4-(3,4-dichlorophenyl)-2-hydrazono-4-phenyl butanamide

Guidance literature:: With hydrazine hydrate; In methanol; for 4h; Reflux;
DOI:10.1002/anie.201403325

Reference yield:

: 1637758-87-2
C₁₄H₁₇Cl₂NO₂

: 1637758-80-5
(R,Z)-N-tert-butyl-4-(3,4-dichlorophenyl)-2-hydrazono-4-phenyl butanamide

Guidance literature:: Multi-step reaction with 3 steps

1: Dess-Martin periodane / dichloromethane / 20 °C

2: chlorobis(ethylene)rhodium(I) dimer; potassium hydroxide; (2,6-bis((R)-tert-butylsulfinyl)phenyl)diphenylphosphine / dichloromethane; water / 12 h / 20 °C / Glovebox; Schlenk technique

3: hydrazine hydrate / methanol / 4 h / Reflux

With chlorobis(ethylene)rhodium(I) dimer; (2,6-bis((R)-tert-butylsulfinyl)phenyl)diphenylphosphine; Dess-Martin periodane; hydrazine hydrate; potassium hydroxide; In methanol; dichloromethane; water;
DOI:10.1002/anie.201403325

Reference yield:

: 62374-02-1
(E)-3,4-dichlorocinnamaldehyde

: 1637758-80-5
(R,Z)-N-tert-butyl-4-(3,4-dichlorophenyl)-2-hydrazono-4-phenyl butanamide

Guidance literature:: Multi-step reaction with 4 steps

1: tin(IV) chloride; pyridine N-oxide / dichloromethane / 4 h / -78 °C

2: Dess-Martin periodane / dichloromethane / 20 °C

3: chlorobis(ethylene)rhodium(I) dimer; potassium hydroxide; (2,6-bis((R)-tert-butylsulfinyl)phenyl)diphenylphosphine / dichloromethane; water / 12 h / 20 °C / Glovebox; Schlenk technique

4: hydrazine hydrate / methanol / 4 h / Reflux

With pyridine N-oxide; chlorobis(ethylene)rhodium(I) dimer; (2,6-bis((R)-tert-butylsulfinyl)phenyl)diphenylphosphine; tin(IV) chloride; Dess-Martin periodane; hydrazine hydrate; potassium hydroxide; In methanol; dichloromethane; water;
DOI:10.1002/anie.201403325