(1R,2S)-1-tert-Butoxycarbonylamino-2-[2-({methylsulfanyl-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-ethyl]-cyclopropanecarboxylic acid tert-butyl ester

Base Information

Chemical Name:(1R,2S)-1-tert-Butoxycarbonylamino-2-[2-({methylsulfanyl-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-ethyl]-cyclopropanecarboxylic acid tert-butyl ester
CAS No.:145235-08-1
Molecular Formula:C₂₄H₃₇N₃O₆S₂
Molecular Weight:527.706
Hs Code.:

(1R,2S)-1-tert-Butoxycarbonylamino-2-[2-({methylsulfanyl-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-ethyl]-cyclopropanecarboxylic acid tert-butyl ester

Synonyms:(1R,2S)-1-tert-Butoxycarbonylamino-2-[2-({methylsulfanyl-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-ethyl]-cyclopropanecarboxylic acid tert-butyl ester

Suppliers and Price of (1R,2S)-1-tert-Butoxycarbonylamino-2-[2-({methylsulfanyl-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-ethyl]-cyclopropanecarboxylic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,2S)-1-tert-Butoxycarbonylamino-2-[2-({methylsulfanyl-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-ethyl]-cyclopropanecarboxylic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,2S)-1-tert-Butoxycarbonylamino-2-[2-({methylsulfanyl-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-ethyl]-cyclopropanecarboxylic acid tert-butyl ester

There total 5 articles about (1R,2S)-1-tert-Butoxycarbonylamino-2-[2-({methylsulfanyl-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-ethyl]-cyclopropanecarboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 2651-15-2
N-[bis(methylthio)methylene]-p-toluenesulfonamide

: 145235-07-0
(2R,3S)-(+)-BOC-cyclo-Orn-OtBu

: 145235-08-1
(1R,2S)-1-tert-Butoxycarbonylamino-2-[2-({methylsulfanyl-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-ethyl]-cyclopropanecarboxylic acid tert-butyl ester

Guidance literature:: In xylene; at 140 ℃;
DOI:10.1016/0040-4039(92)89003-U

Reference yield:

: 145235-06-9
(1R,2R)-1-tert-Butoxycarbonylamino-2-cyanomethyl-cyclopropanecarboxylic acid tert-butyl ester

: 145235-08-1
(1R,2S)-1-tert-Butoxycarbonylamino-2-[2-({methylsulfanyl-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-ethyl]-cyclopropanecarboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / H₂, NH₄OH / Raney-Ni / methanol / 15514.4 Torr

2: 63 percent / xylene / 140 °C

With ammonium hydroxide; hydrogen; nickel; In methanol; xylene;
DOI:10.1016/0040-4039(92)89003-U

Reference yield:

: 143234-52-0
(1R,2S)-(+)-tert-butyl 1--2-(hydroxymethyl)cyclopropane-1-carboxylate

: 145235-08-1
(1R,2S)-1-tert-Butoxycarbonylamino-2-[2-({methylsulfanyl-[(E)-toluene-4-sulfonylimino]-methyl}-amino)-ethyl]-cyclopropanecarboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: NEt₃ / CH₂Cl₂

2: Bu₄NCN / H₂O; benzene / 65 °C

3: 100 percent / H₂, NH₄OH / Raney-Ni / methanol / 15514.4 Torr

4: 63 percent / xylene / 140 °C

With ammonium hydroxide; hydrogen; tetra-n-butylammonium cyanide; triethylamine; nickel; In methanol; dichloromethane; water; xylene; benzene;
DOI:10.1016/0040-4039(92)89003-U