2651-15-2

Basic information

• Product Name: N-[BIS(METHYLTHIO)METHYLENE]-P-TOLUENESULFONAMIDE
• Synonyms: N-[BIS(METHYLTHIO)METHYLENE]-N-TOSYLAMINE;N-[BIS(METHYLTHIO)METHYLENE]-P-TOLUENESULFONAMIDE;Bismethylthiomethylenetoluenesulfonamide;N-(bis(methylthio)methylene)-P-toluene-sulfonamid;N-(4-Methylphenylsulfonyl)imidodithiocarbonic acid dimethyl ester;N-[bis(methylsulfanyl)methylidene]-4-methylbenzenesulfonamide;N-[bis(methylsulfanyl)methylidene]-4-methyl-benzenesulfonamide;N-[bis(methylthio)methylene]-4-methyl-benzenesulfonamide
• CAS NO: 2651-15-2
• Molecular Formula: C₁₀H₁₃NO₂S₃
• Molecular Weight: 275.41
• Product Categories: Sulfur Compounds (for Synthesis);Synthetic Organic Chemistry
• Mol File: 2651-15-2.mol

Chemical Properties

• Melting Point: 109-111 °C(lit.)
• Boiling Point: 419°Cat760mmHg
• Flash Point: 207.2°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 7.64E-07mmHg at 25°C
• Refractive Index: 1.598
• PKA: -6.63±0.50(Predicted)
• CAS DataBase Reference: N-[BIS(METHYLTHIO)METHYLENE]-P-TOLUENESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-[BIS(METHYLTHIO)METHYLENE]-P-TOLUENESULFONAMIDE(2651-15-2)
• EPA Substance Registry System: N-[BIS(METHYLTHIO)METHYLENE]-P-TOLUENESULFONAMIDE(2651-15-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 2651-15-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
N-[BIS(METHYLTHIO)METHYLENE]-P-TOLUENESULFONAMIDE is used as a precursor in the synthesis of bioactive compounds for its potential anticancer and antiparasitic properties. It is valued for its ability to inhibit enzyme activity, which contributes to its potential therapeutic applications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, N-[BIS(METHYLTHIO)METHYLENE]-P-TOLUENESULFONAMIDE is used as a building block for the development of new drugs. Its diverse pharmacological activities make it a promising candidate for further exploration and potential incorporation into novel therapeutic agents.
Used in Drug Development:
N-[BIS(METHYLTHIO)METHYLENE]-P-TOLUENESULFONAMIDE is utilized in drug development for its potential to contribute to the creation of new pharmaceuticals with anti-inflammatory effects. Its role in inhibiting enzyme activity and its potential to be integrated into various biologically active molecules positions it as a key component in the advancement of medicinal treatments.

InChI:InChI=1/C10H13NO2S3/c1-8-4-6-9(7-5-8)16(12,13)11-10(14-2)15-3/h4-7H,1-3H3

Upstream product

• 5706-65-0 dipotassium p-tolylsulfonyl dithiocarbamate 
• 77-78-1 dimethyl sulfate 
• 75-15-0 carbon disulfide 
• 70-55-3 toluene-4-sulfonamide 
• 74-88-4 methyl iodide 

Downstream Products

• 16817-18-8 N--L-glutaminsaeure 
• 16817-16-6 N-Carboxymethyl-S-methyl-N'-p-toluolsulfonyl-isothioharnstoff 
• 16882-20-5 (+/-)-N--alanin 
• 10425-02-2 N-Tosyl-α,α-diacetyl-thioacetimidsaeure-methylester 
• 10425-03-3 2-cyano-3-methylthio-3-p-toluenesulfonylaminopropenenitrile 
• 71767-01-6 N-(4-methyl-spiro[1,3-diaza-bicyclo[3.3.1]non-2-ene-6,2'-[1,3]dioxolan]-2-yl)-toluene-4-sulfonamide 
• 127933-49-7 2,2'-bis(tosylamino)-5,5'(6,6')-bibenzimidazole 
• 139458-87-0 S-Methyl-S'-trimethylsilylmethyl N-(p-toluenesulfonyl)dithioiminocarbonate 
• 139474-76-3 S,S'-Bis(trimethylsilylmethyl) N-(p-toluenesulfonyl)dithioiminocarbonate 
• 137777-75-4 N-p-toluenesulfonyl-N'-trimethylsilylmethyl-S-methylisothiourea 
• 77153-08-3 S-methyl-N-<2-(benzoylamino)ethyl>-N'-tosylisothiourea 
• 77153-07-2 S-methyl-N-<2-<(tert-butoxycarbonyl)amino>ethyl>-N'-tosylisothiourea 
• 134577-10-9 N-(5-Amino-[1,3,4]thiadiazol-2-yl)-4-methyl-benzenesulfonamide 
• 148854-63-1 N-[1-{[(2R,3S,5R)-3-Hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl]-amino}-1-methylsulfanyl-meth-(Z)-ylidene]-4-methyl-benzenesulfonamide 

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PYRIDYL GUANIDINE ANTI-ULCER AGENTS

Compounds of the formula STR1 wherein R 1 is a straight or branched chain alkynyl group containing from 3 to 9 carbon atoms, inclusive; R 2 is hydrogen, hydroxy, cyano, (lower)alkyl, (lower) alkoxy, halogen or amino; n is 2 or 3; X is NR 3 or CHR 3 ; R 3