Ethyl 2-(2,4-bis(trifluoromethyl)phenyl)-2-oxoacetate

Base Information

• Chemical Name: Ethyl 2-(2,4-bis(trifluoromethyl)phenyl)-2-oxoacetate
• CAS No.: 306936-81-2
• Molecular Formula: C₁₂H₈F₆O₃
• Molecular Weight: 314.184
• Hs Code.: 2918300090
• European Community (EC) Number: 692-193-9
• DSSTox Substance ID: DTXSID80381905
• Wikidata: Q82173087
• Mol file: 306936-81-2.mol

Synonyms:306936-81-2;Ethyl 2-(2,4-bis(trifluoromethyl)phenyl)-2-oxoacetate;ethyl 2-[2,4-bis(trifluoromethyl)phenyl]-2-oxoacetate;(2,4-Bis-trifluoromethyl-phenyl)-oxo-acetic acid ethyl ester;DTXSID80381905;MFCD01934869;AKOS015996662;CS-0361369;FT-0625906;Ethyl [2,4-bis(trifluoromethyl)phenyl](oxo)acetate;(2,4-Bis-trifluoromethylphenyl)-oxoacetic acid ethyl ester

Chemical Property of Ethyl 2-(2,4-bis(trifluoromethyl)phenyl)-2-oxoacetate

Chemical Property:

• Vapor Pressure: 0.00318mmHg at 25°C
• Refractive Index: 1.424
• Boiling Point: 283.3°C at 760 mmHg
• Flash Point: 121.3°C
• PSA: 43.37000
• Density: 1.399g/cm³
• LogP: 3.47000
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 4
• Exact Mass: 314.03776309
• Heavy Atom Count: 21
• Complexity: 401

Purity/Quality:

97% ^*data from raw suppliers

(2,4-Bis-trifluoromethyl-phenyl)-oxo-aceticacidethylester ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C(=O)C1=C(C=C(C=C1)C(F)(F)F)C(F)(F)F

Technology Process of Ethyl 2-(2,4-bis(trifluoromethyl)phenyl)-2-oxoacetate

There total 1 articles about Ethyl 2-(2,4-bis(trifluoromethyl)phenyl)-2-oxoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

oxalic acid diethyl ester (95-92-1) + 1-bromo-2,4-di(trifluoromethyl)benzene (327-75-3) → (2,4-bis-trifluoromethyl-phenyl)-oxo-acetic acid ethyl ester (306936-81-2)

Guidance literature:

1-bromo-2,4-di(trifluoromethyl)benzene; With magnesium; In diethyl ether;

oxalic acid diethyl ester; In diethyl ether; at -78 ℃;

DOI:10.1016/S0960-894X(02)00099-9

Reference yield:

(2,4-bis-trifluoromethyl-phenyl)-oxo-acetic acid ethyl ester (306936-81-2) → (2,4-bis-trifluoromethyl-phenyl)-oxo-acetic acid (467435-10-5)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran;

DOI:10.1016/S0960-894X(02)00099-9

Reference yield:

(2,4-bis-trifluoromethyl-phenyl)-oxo-acetic acid ethyl ester (306936-81-2) → (2,4-bis-trifluoromethyl-phenyl)-[(5-chloro-2-methoxy-phenyl)-hydrazono]-acetic acid

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaOH / tetrahydrofuran

2: ethanol / Heating

With sodium hydroxide; In tetrahydrofuran; ethanol;

DOI:10.1016/S0960-894X(02)00099-9

upstream raw materials:

oxalic acid diethyl ester

1-bromo-2,4-di(trifluoromethyl)benzene

Downstream raw materials:

(2,4-bis-trifluoromethyl-phenyl)-oxo-acetic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 306936-81-2 ETHYL 2-[2,4-BIS(TRIFLUOROMETHYL)PHENYL]-2-OXOACETATE

Send

Send

Metric Ton KG G Pound L ML

Send

Send