N-(3-NITROPHENYL)-N-PHENYL ACETAMIDE

Base Information

• Chemical Name: N-(3-NITROPHENYL)-N-PHENYL ACETAMIDE
• CAS No.: 32047-90-8
• Molecular Formula: C14H12 N2 O3
• Molecular Weight: 256.26
• Mol file: 32047-90-8.mol

Synonyms:Acetanilide,3'-nitro-N-phenyl- (6CI,7CI,8CI)

Chemical Property of N-(3-NITROPHENYL)-N-PHENYL ACETAMIDE

Chemical Property:

• Melting Point: 71 °C
• Boiling Point: 495.0±28.0 °C(Predicted)
• PKA: -5.67±0.50(Predicted)
• PSA: 66.13000
• Density: 1.284±0.06 g/cm3(Predicted)
• LogP: 3.80260

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(3-NITROPHENYL)-N-PHENYL ACETAMIDE

There total 5 articles about N-(3-NITROPHENYL)-N-PHENYL ACETAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

iodobenzene (591-50-4) + N-(3-nitrophenyl)acetanilide (122-28-1) → N-(3-nitro-phenyl)-N-phenyl-acetamide (32047-90-8)

Guidance literature:

With potassium carbonate; at 180 ℃;

DOI:10.1016/0040-4039(95)01880-Q

Reference yield: 18.0%

m-nitrobenzene boronic acid (13331-27-6) + Acetanilid (103-84-4) → N-(3-nitro-phenyl)-N-phenyl-acetamide (32047-90-8)

Guidance literature:

With copper diacetate; triethylamine; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4039(98)01735-3

Reference yield:

C6H4LiNO2 → N-(3-nitro-phenyl)-N-phenyl-acetamide (32047-90-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) trimethyl borate; 2.) H(+)

2: 18 percent / cupric acetate, triethylamine / CH₂Cl₂ / Ambient temperature

With Trimethyl borate; copper diacetate; hydrogen cation; triethylamine; In dichloromethane;

DOI:10.1016/S0040-4039(98)01735-3

upstream raw materials:

3-nitro-N-phenylaniline

acetic anhydride

iodobenzene

N-(3-nitrophenyl)acetanilide

Downstream raw materials:

N-phenyl-N,N'-m-phenylene-bis-acetamide

N-(3-amino-phenyl)-N-phenyl-acetamide

Refernces

• 1、 Ito, Akihiro,Saito, Takeshi,Tanaka, Kazuyoshi,Yamabe, Tokio. "Synthesis of oligo(m-aniline)". . p. 8809 - 8812. Retrieved 2007/10/02.