6-(4-Bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxamide

Base Information

Chemical Name:6-(4-Bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxamide
CAS No.:1072708-49-6
Molecular Formula:C₂₅H₁₉BrCl₂N₂O₃
Molecular Weight:546.247
Hs Code.:

Synonyms:6-(4-Bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxamide

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Chemical Property of 6-(4-Bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxamide

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Technology Process of 6-(4-Bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxamide

There total 2 articles about 6-(4-Bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1072708-44-1
6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxylic acid diisopropylamine salt

: 1072708-49-6
6-(4-Bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxamide

Guidance literature:: 6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxylic acid diisopropylamine salt; With oxalyl dichloride; N,N-dimethyl-formamide; In ethyl acetate; at 20 - 25 ℃; for 0.583333 - 1.08333h;

With ammonia; In n-heptane; water; ethyl acetate; at -30 - 20 ℃; for 2.5h; Product distribution / selectivity;

Reference yield:

: 1072708-54-3
6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carbaldehyde oxime

: 1072708-49-6
6-(4-Bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxamide

Guidance literature:: 6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carbaldehyde oxime; With methanesulfonic acid; water; at 100 ℃; for 4h;

With water; sodium hydrogencarbonate; In ethyl acetate; Product distribution / selectivity;

Reference yield:

: 1009071-34-4
tert-butyl 3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

: 1072708-49-6
6-(4-Bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxamide

: 1072709-38-6
6-[2-chloro-4-(3-methyl-1H-pyrazol-4-yl)phenyl]-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxamide

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1-methyl-pyrrolidin-2-one; water; iso-butanol; at 100 ℃; for 4h;