(E)-ethyl 2-(4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2-(8bH)-ylidene)acetate

Base Information

• Chemical Name: (E)-ethyl 2-(4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2-(8bH)-ylidene)acetate
• CAS No.: 1356266-06-2
• Molecular Formula: C₁₉H₁₇NO₄S
• Molecular Weight: 355.414
• Mol file: 1356266-06-2.mol

Synonyms:(E)-ethyl 2-(4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2-(8bH)-ylidene)acetate

Chemical Property of (E)-ethyl 2-(4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2-(8bH)-ylidene)acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-ethyl 2-(4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2-(8bH)-ylidene)acetate

There total 3 articles about (E)-ethyl 2-(4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2-(8bH)-ylidene)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3-phenylbenzo[d]isothiazole-1,1-dioxide (53440-57-6) + ethyl 2,3-butadienoate (14369-81-4) → (E)-ethyl 2-(4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2-(8bH)-ylidene)acetate (1356266-06-2)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In toluene; at 20 ℃; for 24h; regioselective reaction; Inert atmosphere;

DOI:10.1039/c2cc16055b

Reference yield: 52.0%

3-phenylbenzo[d]isothiazole-1,1-dioxide (53440-57-6) + ethyl 2,3-butadienoate (14369-81-4) → ethyl 9b-phenyl-1,9b-dihydrobenzo[d]pyrrolo[1,2-b]isothiazole-3-carboxylate 5,5-dioxide (1356266-07-3) + ethyl 9b-phenyl-3,9b-dihydrobenzo[d]pyrrolo[1,2-b]isothiazole-1-carboxylate 5,5-dioxide (1356266-08-4) + (E)-ethyl 2-(4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2-(8bH)-ylidene)acetate (1356266-06-2)

Guidance literature:

With tributylphosphine; In toluene; at 20 ℃; for 72h; regioselective reaction; Inert atmosphere;

DOI:10.1039/c2cc16055b

Reference yield: 41.0%

3-phenylbenzo[d]isothiazole-1,1-dioxide (53440-57-6) + ethyl 2,3-butadienoate (14369-81-4) → ethyl 9b-phenyl-1,9b-dihydrobenzo[d]pyrrolo[1,2-b]isothiazole-3-carboxylate 5,5-dioxide (1356266-07-3) + (E)-ethyl 2-(4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2-(8bH)-ylidene)acetate (1356266-06-2)

Guidance literature:

With Hexamethylphosphorous triamide; In toluene; at 20 ℃; for 72h; regioselective reaction; Inert atmosphere;

DOI:10.1039/c2cc16055b

upstream raw materials:

3-phenylbenzo[d]isothiazole-1,1-dioxide

ethyl 2,3-butadienoate