2-thioxo-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one

Base Information

Chemical Name:2-thioxo-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one
CAS No.:31895-77-9
Molecular Formula:C₆H₄N₂OS₂
Molecular Weight:184.243
Hs Code.:2934999090
DSSTox Substance ID:DTXSID30588048
Nikkaji Number:J2.961.025H
Wikidata:Q82480533
Mol file:31895-77-9.mol

Synonyms:31895-77-9;2-thioxo-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one;2-sulfanyl-3H,4H-thieno[3,2-d]pyrimidin-4-one;2-sulfanylidene-1H-thieno[3,2-d]pyrimidin-4-one;2-mercaptothieno[3,2-d]pyrimidin-4(3H)-one;SCHEMBL2588876;SCHEMBL8945519;2-mercaptothienopyrimidin-4-one;DTXSID30588048;STL141099;AKOS000124031;AKOS001466125;AKOS006242451;MCULE-6438943455;4-oxothieno[3,2-d]pyrimidine-2-thione;DA-27410;CS-0088170;EN300-30655;4-hydroxy-3H-thieno[3,2-d]pyrimidine-2-thione;AB00990801-01;Z315923754;2-sulfanylidene-1H,2H,3H,4H-thieno[3,2-d]pyrimidin-4-one;2-Sulfanylidene-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one

Suppliers and Price of 2-thioxo-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-thioxo-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one

Chemical Property:

PSA：112.79000
LogP:1.27330
XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:183.97650510
Heavy Atom Count:11
Complexity:219

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CSC2=C1NC(=S)NC2=O

Technology Process of 2-thioxo-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one

There total 4 articles about 2-thioxo-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 178675-17-7
methyl 3-[3-(1-phenylmethanoyl)thioureido]thiophene-2-carboxylate

: 31895-77-9
2-thioxo-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one

Guidance literature:: With sodium hydroxide; In methanol; at 20 ℃; for 4h;

Reference yield:

: 22288-78-4
Methyl 3-aminothiophene-2-carboxylate

: 31895-77-9
2-thioxo-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetone / 0.5 h / Reflux

1.2: 2 h / Reflux

2.1: potassium hydroxide / ethanol / 2 h / Reflux

2.2: 1 h / 20 °C

With potassium hydroxide; In ethanol; acetone;
DOI:10.1002/jhet.549