(E)-3-methyl-4-tetradecylidene-1-p-tolylpyrrolidine-2,5-dione

Base Information

• Chemical Name: (E)-3-methyl-4-tetradecylidene-1-p-tolylpyrrolidine-2,5-dione
• CAS No.: 190728-73-5
• Molecular Formula: C₂₆H₃₉NO₂
• Molecular Weight: 397.601
• Mol file: 190728-73-5.mol

Synonyms:(E)-3-methyl-4-tetradecylidene-1-p-tolylpyrrolidine-2,5-dione

Chemical Property of (E)-3-methyl-4-tetradecylidene-1-p-tolylpyrrolidine-2,5-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-3-methyl-4-tetradecylidene-1-p-tolylpyrrolidine-2,5-dione

There total 3 articles about (E)-3-methyl-4-tetradecylidene-1-p-tolylpyrrolidine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

(E)-3-tetradecylidene-1-p-tolyl-pyrrolidine-2,5-dione (558480-31-2) + methyl iodide (74-88-4) → (E)-3-methyl-4-tetradecylidene-1-p-tolylpyrrolidine-2,5-dione (190728-73-5)

Guidance literature:

(E)-3-tetradecylidene-1-p-tolyl-pyrrolidine-2,5-dione; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h;

methyl iodide; In tetrahydrofuran; at 0 - 20 ℃; for 3h; Further stages.;

DOI:10.1021/jo801284r

Reference yield:

3-methyl-1-(p-tolyl)-1H-pyrrole-2,5-dione (3120-12-5) → (E)-3-methyl-4-tetradecylidene-1-p-tolylpyrrolidine-2,5-dione (190728-73-5)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / 2 h / Heating

2: acetic acid / 18 h / Heating

In acetic acid;

DOI:10.1021/jo9700383

Reference yield:

myristylaldehyde (124-25-4,511542-15-7) + 3-Methyl-1-p-tolyl-4-(triphenyl-λ5-phosphanylidene)-pyrrolidine-2,5-dione (190728-72-4) → 3-(Z)-tetradecylidene-4-methyl-N-p-tolylsuccinimide + (E)-3-methyl-4-tetradecylidene-1-p-tolylpyrrolidine-2,5-dione (190728-73-5)

Guidance literature:

In acetic acid; for 18h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Heating;

DOI:10.1021/jo9700383

upstream raw materials:

myristylaldehyde

3-Methyl-1-p-tolyl-4-(triphenyl-λ⁵-phosphanylidene)-pyrrolidine-2,5-dione

3-methyl-1-(p-tolyl)-1H-pyrrole-2,5-dione

(E)-3-tetradecylidene-1-p-tolyl-pyrrolidine-2,5-dione

Downstream raw materials:

3-methyl-4-tetradecyl-1-p-tolyl-1H-pyrrole-2,5-dione