3-O-benzyl-2-O-[4-(benzyloxy)phenyl-2,3,4-tri-O-benzyl-β-D-glucopyranoside-6-benzylphosphoryl]-5,6-O-isopropylidene-L-ascorbic acid

Base Information

Chemical Name:3-O-benzyl-2-O-[4-(benzyloxy)phenyl-2,3,4-tri-O-benzyl-β-D-glucopyranoside-6-benzylphosphoryl]-5,6-O-isopropylidene-L-ascorbic acid
CAS No.:180297-91-0
Molecular Formula:C₆₃H₆₃O₁₅P
Molecular Weight:1091.16
Hs Code.:

Synonyms:3-O-benzyl-2-O-[4-(benzyloxy)phenyl-2,3,4-tri-O-benzyl-β-D-glucopyranoside-6-benzylphosphoryl]-5,6-O-isopropylidene-L-ascorbic acid

Suppliers and Price of 3-O-benzyl-2-O-[4-(benzyloxy)phenyl-2,3,4-tri-O-benzyl-β-D-glucopyranoside-6-benzylphosphoryl]-5,6-O-isopropylidene-L-ascorbic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-O-benzyl-2-O-[4-(benzyloxy)phenyl-2,3,4-tri-O-benzyl-β-D-glucopyranoside-6-benzylphosphoryl]-5,6-O-isopropylidene-L-ascorbic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-O-benzyl-2-O-[4-(benzyloxy)phenyl-2,3,4-tri-O-benzyl-β-D-glucopyranoside-6-benzylphosphoryl]-5,6-O-isopropylidene-L-ascorbic acid

There total 10 articles about 3-O-benzyl-2-O-[4-(benzyloxy)phenyl-2,3,4-tri-O-benzyl-β-D-glucopyranoside-6-benzylphosphoryl]-5,6-O-isopropylidene-L-ascorbic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Phosphorous acid benzyl ester (R)-4-benzyloxy-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-oxo-2,5-dihydro-furan-3-yl ester (2R,3R,4S,5R,6S)-3,4,5-tris-benzyloxy-6-(4-benzyloxy-phenoxy)-tetrahydro-pyran-2-ylmethyl ester

: 180297-91-0
3-O-benzyl-2-O-[4-(benzyloxy)phenyl-2,3,4-tri-O-benzyl-β-D-glucopyranoside-6-benzylphosphoryl]-5,6-O-isopropylidene-L-ascorbic acid

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 - 20 ℃; for 1h;
DOI:10.1016/0008-6215(96)00043-2

Reference yield:

: 100-44-7
benzyl chloride

: 180297-91-0
3-O-benzyl-2-O-[4-(benzyloxy)phenyl-2,3,4-tri-O-benzyl-β-D-glucopyranoside-6-benzylphosphoryl]-5,6-O-isopropylidene-L-ascorbic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / NaOH / dimethylsulfoxide / 42 h / 20 °C

2: 60 percent / HCl; H₂O / tetrahydrofuran / 6 h / 20 °C

3: 1H-tetrazole / CH₂Cl₂ / 22 h / 20 °C

4: 3.2 g / m-chloroperoxybenzoic acid / CH₂Cl₂ / 1 h / 0 - 20 °C

With 1H-tetrazole; hydrogenchloride; sodium hydroxide; water; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide; 1: Etherification / 2: Hydrolysis / 3: Condensation / 4: Oxidation;
DOI:10.1016/0008-6215(96)00043-2

Reference yield:

: 86404-07-1
O³-benzyl-O⁵,O⁶-(1-methylethylidene)-L-ascorbic acid

: 180297-91-0
3-O-benzyl-2-O-[4-(benzyloxy)phenyl-2,3,4-tri-O-benzyl-β-D-glucopyranoside-6-benzylphosphoryl]-5,6-O-isopropylidene-L-ascorbic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 97 percent / 1H-tetrazole / CH₂Cl₂ / 1 h / 20 °C

2: 1H-tetrazole / CH₂Cl₂ / 22 h / 20 °C

3: 3.2 g / m-chloroperoxybenzoic acid / CH₂Cl₂ / 1 h / 0 - 20 °C

With 1H-tetrazole; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; 1: Condensation / 2: Condensation / 3: Oxidation;
DOI:10.1016/0008-6215(96)00043-2