N-tert-butoxycarbonyl-2-(N-tert-butoxycarbonyl-2-phenyl-1H-pyrrol-5-yl)-1H-indole

Base Information

Chemical Name:N-tert-butoxycarbonyl-2-(N-tert-butoxycarbonyl-2-phenyl-1H-pyrrol-5-yl)-1H-indole
CAS No.:1146731-34-1
Molecular Formula:C₂₈H₃₀N₂O₄
Molecular Weight:458.557
Hs Code.:

Synonyms:N-tert-butoxycarbonyl-2-(N-tert-butoxycarbonyl-2-phenyl-1H-pyrrol-5-yl)-1H-indole

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Chemical Property of N-tert-butoxycarbonyl-2-(N-tert-butoxycarbonyl-2-phenyl-1H-pyrrol-5-yl)-1H-indole

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Technology Process of N-tert-butoxycarbonyl-2-(N-tert-butoxycarbonyl-2-phenyl-1H-pyrrol-5-yl)-1H-indole

There total 3 articles about N-tert-butoxycarbonyl-2-(N-tert-butoxycarbonyl-2-phenyl-1H-pyrrol-5-yl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1146731-30-7
N-tert-butoxycarbonyl-2-(N-tert-butoxycarbonyl-2-bromo-1H-pyrrol-5-yl)-1H-indole

: 98-80-6
phenylboronic acid

: 1146731-34-1
N-tert-butoxycarbonyl-2-(N-tert-butoxycarbonyl-2-phenyl-1H-pyrrol-5-yl)-1H-indole

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; water; toluene; at 100 ℃; for 3h; Inert atmosphere;
DOI:10.1055/s-0030-1258284

Reference yield: 69.0%

: 117657-38-2
2,5-dibromopyrrole-1-carboxylic acid tert-butyl ester

: 213318-44-6
N-Boc-indole-2-boronic acid

: 98-80-6
phenylboronic acid

: 1146731-34-1
N-tert-butoxycarbonyl-2-(N-tert-butoxycarbonyl-2-phenyl-1H-pyrrol-5-yl)-1H-indole

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium chloride; sodium carbonate; In ethanol; water; toluene; at 100 ℃; for 3h; Inert atmosphere;
DOI:10.1021/ol900358n

Reference yield: 41.0%

: 1146732-16-2
N-tert-butoxycarbonyl-5-iodo-2-phenyl-1H-pyrrole

: 213318-44-6
N-Boc-indole-2-boronic acid

: 1146731-34-1
N-tert-butoxycarbonyl-2-(N-tert-butoxycarbonyl-2-phenyl-1H-pyrrol-5-yl)-1H-indole

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; water; at 20 - 85 ℃; for 15h; Inert atmosphere;
DOI:10.1055/s-0030-1258284