C₃₀H₄₈O₄

Base Information

• Chemical Name: C₃₀H₄₈O₄
• CAS No.: 1360999-03-6
• Molecular Formula: C₃₀H₄₈O₄
• Molecular Weight: 472.709
• Mol file: 1360999-03-6.mol

Synonyms:C₃₀H₄₈O₄

Chemical Property of C₃₀H₄₈O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₄₈O₄

There total 6 articles about C₃₀H₄₈O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

C28H42O5 (1360999-01-4) + ethylmagnesium bromide (925-90-6) → C30H48O4 (1360999-03-6)

Guidance literature:

In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.bmcl.2011.12.137

Reference yield:

Bicyclo<2.2.2>octane-1,4-dimethanol (826-45-9) → C30H48O4 (1360999-03-6)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 - 20 °C / Inert atmosphere

1.2: 0 - 20 °C / Inert atmosphere

2.1: pyridinium chlorochromate / dichloromethane / 2.5 h / 20 °C

3.1: sodium hydride / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

3.2: 0 - 20 °C / Inert atmosphere

4.1: palladium on activated charcoal; hydrogen / ethyl acetate / 1.5 h / 20 °C

5.1: tetrahydrofuran / 20 °C / Inert atmosphere

With palladium on activated charcoal; hydrogen; sodium hydride; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; 3.1: Horner-Wadsworth-Emmons type reaction / 3.2: Horner-Wadsworth-Emmons type reaction;

DOI:10.1016/j.bmcl.2011.12.137

Reference yield:

Bicyclo<2.2.2.>octan-1,4-dicarbonsauere-ethylester (1659-75-2) → C30H48O4 (1360999-03-6)

Guidance literature:

Multi-step reaction with 6 steps

1.1: lithium aluminium tetrahydride / diethyl ether / 4 h / Inert atmosphere; Reflux

2.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 - 20 °C / Inert atmosphere

2.2: 0 - 20 °C / Inert atmosphere

3.1: pyridinium chlorochromate / dichloromethane / 2.5 h / 20 °C

4.1: sodium hydride / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

4.2: 0 - 20 °C / Inert atmosphere

5.1: palladium on activated charcoal; hydrogen / ethyl acetate / 1.5 h / 20 °C

6.1: tetrahydrofuran / 20 °C / Inert atmosphere

With lithium aluminium tetrahydride; palladium on activated charcoal; hydrogen; sodium hydride; pyridinium chlorochromate; In tetrahydrofuran; diethyl ether; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; 4.1: Horner-Wadsworth-Emmons type reaction / 4.2: Horner-Wadsworth-Emmons type reaction;

DOI:10.1016/j.bmcl.2011.12.137

upstream raw materials:

C₂₈H₃₈O₅

C₂₈H₄₂O₅

ethylmagnesium bromide

C₂₂H₃₂O₄