3-[4-(2-Chloro-6-fluorobenzyl)piperazino]propylamine

Base Information

Chemical Name:3-[4-(2-Chloro-6-fluorobenzyl)piperazino]propylamine
CAS No.:306934-74-7
Molecular Formula:C14H21 Cl F N3
Molecular Weight:285.79
Hs Code.:2933599090
DSSTox Substance ID:DTXSID40381446
Wikidata:Q82172266
Mol file:306934-74-7.mol

Synonyms:306934-74-7;3-[4-(2-Chloro-6-fluorobenzyl)piperazino]propylamine;3-[4-[(2-chloro-6-fluorophenyl)methyl]piperazin-1-yl]propan-1-amine;3-(4-(2-Chloro-6-fluorobenzyl)piperazin-1-yl)propan-1-amine;SCHEMBL656160;DTXSID40381446;CEOASWXTZYXWTP-UHFFFAOYSA-N;MFCD02677685;AKOS027380291;FT-0614828;A820492;J-511468;3-[4-(2-chloro-6-fluorobenzyl)piperazino]propylamine, AldrichCPR

Suppliers and Price of 3-[4-(2-Chloro-6-fluorobenzyl)piperazino]propylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-[4-(2-CHLORO-6-FLUOROBENZYL)PIPERAZINO]PROPYLAMINE 95.00%
1G
$ 839.22

American Custom Chemicals Corporation
3-[4-(2-CHLORO-6-FLUOROBENZYL)PIPERAZINO]PROPYLAMINE 95.00%
250MG
$ 654.89

Total 8 raw suppliers

Chemical Property of 3-[4-(2-Chloro-6-fluorobenzyl)piperazino]propylamine

Chemical Property:

Vapor Pressure:6.07E-06mmHg at 25°C
Refractive Index:1.553
Boiling Point:378.9°C at 760 mmHg
Flash Point:183°C
PSA：32.50000
Density:1.186g/cm³
LogP:2.52160
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:285.1408035
Heavy Atom Count:19
Complexity:259

Purity/Quality:

97% ^*data from raw suppliers

3-[4-(2-CHLORO-6-FLUOROBENZYL)PIPERAZINO]PROPYLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 34
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCCN)CC2=C(C=CC=C2Cl)F

Technology Process of 3-[4-(2-Chloro-6-fluorobenzyl)piperazino]propylamine

There total 1 articles about 3-[4-(2-Chloro-6-fluorobenzyl)piperazino]propylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1189166-30-0
{[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]propyl}carbamic acid benzyl ester

: 306934-74-7
{[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]}propylamine

Guidance literature:: {[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]propyl}carbamic acid benzyl ester; With trimethylsilyl iodide; In acetonitrile; at 20 ℃; for 0.25h;

With methanol; In acetonitrile; for 0.166667h;
DOI:10.1016/j.bmc.2009.06.069

Reference yield:

: 306934-74-7
{[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]}propylamine

: 3900-93-4
2-cyclopentyl-2-phenylacetic acid

: N-{3-[4-(2-chloro-6-fluorobenzyl)-1-piperazinyl]propyl}-2-cyclopentyl-2-phenylacetamide

Guidance literature:: 2-cyclopentyl-2-phenylacetic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; for 1.5h; Heating / reflux;

{[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]}propylamine; In tetrahydrofuran; at 20 ℃; for 8h;