{[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]propyl}carbamic acid benzyl ester

Base Information

Chemical Name:{[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]propyl}carbamic acid benzyl ester
CAS No.:1189166-30-0
Molecular Formula:C₂₂H₂₇ClFN₃O₂
Molecular Weight:419.927
Hs Code.:

Synonyms:{[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]propyl}carbamic acid benzyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of {[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]propyl}carbamic acid benzyl ester

Chemical Property:

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MSDS Files:: SDS file from LookChem

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Technology Process of {[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]propyl}carbamic acid benzyl ester

There total 1 articles about {[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]propyl}carbamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 215655-20-2
1-(2-chloro-6-fluorobenzyl)piperazine

: 39945-54-5
benzyl N-(3-bromopropyl)carbamate

: 1189166-30-0
{[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]propyl}carbamic acid benzyl ester

Guidance literature:: With potassium carbonate; In acetonitrile; for 4h; Reflux; Inert atmosphere;
DOI:10.1016/j.bmc.2009.06.069

Reference yield: 99.0%

: 1189166-30-0
{[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]propyl}carbamic acid benzyl ester

: 306934-74-7
{[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]}propylamine

Guidance literature:: {[3-(4-(2-chloro-6-fluoro-benzyl)piperazin-1-yl)]propyl}carbamic acid benzyl ester; With trimethylsilyl iodide; In acetonitrile; at 20 ℃; for 0.25h;

With methanol; In acetonitrile; for 0.166667h;
DOI:10.1016/j.bmc.2009.06.069