1-[3-(p-methoxybenzyloxy)-4-methoxyphenyl]-3-(3,4,5-trimethoxyphenyl)propenone

Base Information

• Chemical Name: 1-[3-(p-methoxybenzyloxy)-4-methoxyphenyl]-3-(3,4,5-trimethoxyphenyl)propenone
• CAS No.: 891188-92-4
• Molecular Formula: C₂₇H₂₈O₇
• Molecular Weight: 464.515
• Mol file: 891188-92-4.mol

Synonyms:1-[3-(p-methoxybenzyloxy)-4-methoxyphenyl]-3-(3,4,5-trimethoxyphenyl)propenone

Chemical Property of 1-[3-(p-methoxybenzyloxy)-4-methoxyphenyl]-3-(3,4,5-trimethoxyphenyl)propenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-[3-(p-methoxybenzyloxy)-4-methoxyphenyl]-3-(3,4,5-trimethoxyphenyl)propenone

There total 1 articles about 1-[3-(p-methoxybenzyloxy)-4-methoxyphenyl]-3-(3,4,5-trimethoxyphenyl)propenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

methyl (3,4,5-trimethoxyphenyl) ketone (1136-86-3) + 4-methoxy-3-((4-methoxybenzyl)oxy)benzaldehyde (72785-29-6) → 1-[3-(p-methoxybenzyloxy)-4-methoxyphenyl]-3-(3,4,5-trimethoxyphenyl)propenone (891188-92-4)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 60 ℃; for 5h;

DOI:10.1016/j.bmc.2006.02.001

Reference yield: 83.0%

1-[3-(p-methoxybenzyloxy)-4-methoxyphenyl]-3-(3,4,5-trimethoxyphenyl)propenone (891188-92-4) → (E)-2,3-epoxy-3-[3-(p-methoxybenzyloxy)-4-methoxyphenyl]-1-(3,4,5-trimethoxyphenyl)propenone

Guidance literature:

With sodium hydroxide; dihydrogen peroxide; In ethanol; water; at 0 - 20 ℃;

DOI:10.1016/j.bmc.2006.02.001

Reference yield:

1-[3-(p-methoxybenzyloxy)-4-methoxyphenyl]-3-(3,4,5-trimethoxyphenyl)propenone (891188-92-4) → 4-(3-hydroxy-4-methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)isoxazole

Guidance literature:

Multi-step reaction with 2 steps

1.1: 83 percent / H₂O₂; NaOH / ethanol; H₂O / 0 - 20 °C

2.1: BF₃*Et₂O / tetrahydrofuran / 0.75 h / Heating

2.2: 32 percent / pyridine; hydroxylamine hydrochloride / ethanol / 6 h / Heating

With sodium hydroxide; boron trifluoride diethyl etherate; dihydrogen peroxide; In tetrahydrofuran; ethanol; water;

DOI:10.1016/j.bmc.2006.02.001

upstream raw materials:

methyl (3,4,5-trimethoxyphenyl) ketone

4-methoxy-3-((4-methoxybenzyl)oxy)benzaldehyde