(6Z,10E,14E,18E)-3-Acetoxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-10,15,19,23-tetramethyl-2-methylene-tetracosa-6,10,14,18,22-pentaenoic acid methyl ester

Base Information

Chemical Name:(6Z,10E,14E,18E)-3-Acetoxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-10,15,19,23-tetramethyl-2-methylene-tetracosa-6,10,14,18,22-pentaenoic acid methyl ester
CAS No.:854735-71-0
Molecular Formula:C₄₉H₇₀O₅Si
Molecular Weight:767.177
Hs Code.:

(6Z,10E,14E,18E)-3-Acetoxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-10,15,19,23-tetramethyl-2-methylene-tetracosa-6,10,14,18,22-pentaenoic acid methyl ester

Synonyms:(6Z,10E,14E,18E)-3-Acetoxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-10,15,19,23-tetramethyl-2-methylene-tetracosa-6,10,14,18,22-pentaenoic acid methyl ester

Suppliers and Price of (6Z,10E,14E,18E)-3-Acetoxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-10,15,19,23-tetramethyl-2-methylene-tetracosa-6,10,14,18,22-pentaenoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (6Z,10E,14E,18E)-3-Acetoxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-10,15,19,23-tetramethyl-2-methylene-tetracosa-6,10,14,18,22-pentaenoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (6Z,10E,14E,18E)-3-Acetoxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-10,15,19,23-tetramethyl-2-methylene-tetracosa-6,10,14,18,22-pentaenoic acid methyl ester

There total 4 articles about (6Z,10E,14E,18E)-3-Acetoxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-10,15,19,23-tetramethyl-2-methylene-tetracosa-6,10,14,18,22-pentaenoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 854735-57-2
(6Z,10E,14E,18E)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-3-hydroxy-10,15,19,23-tetramethyl-2-methylene-tetracosa-6,10,14,18,22-pentaenoic acid methyl ester

: 75-36-5
acetyl chloride

: 854735-71-0
(6Z,10E,14E,18E)-3-Acetoxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-10,15,19,23-tetramethyl-2-methylene-tetracosa-6,10,14,18,22-pentaenoic acid methyl ester

Guidance literature:: With pyridine; dmap; In dichloromethane; at 0 ℃; for 2h;
DOI:10.1021/ja050340q

Reference yield:

: 854735-70-9
(4Z,8E,12E,16E)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-8,13,17,21-tetramethyl-docosa-4,8,12,16,20-pentaen-1-ol

: 854735-71-0
(6Z,10E,14E,18E)-3-Acetoxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-10,15,19,23-tetramethyl-2-methylene-tetracosa-6,10,14,18,22-pentaenoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 82 percent / Dess-Martin periodinane; pyridine / CH₂Cl₂ / 1 h / 0 °C

2.1: DIBAL-H / tetrahydrofuran; hexane; hexamethylphosphoric acid triamide / 2.5 h / 0 °C

2.2: 82 percent / tetrahydrofuran; hexane; hexamethylphosphoric acid triamide / 0 - 20 °C

3.1: 94 percent / pyridine; DMAP / CH₂Cl₂ / 2 h / 0 °C

With pyridine; dmap; diisobutylaluminium hydride; Dess-Martin periodane; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; dichloromethane;
DOI:10.1021/ja050340q

Reference yield:

: (4Z,8E,12E,16E)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-8,13,17,21-tetramethyl-docosa-4,8,12,16,20-pentaenoic acid ethyl ester

: 854735-71-0
(6Z,10E,14E,18E)-3-Acetoxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-10,15,19,23-tetramethyl-2-methylene-tetracosa-6,10,14,18,22-pentaenoic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: 91 percent / DIBAL-H / tetrahydrofuran; hexane / 5 h / 0 °C

2.1: 82 percent / Dess-Martin periodinane; pyridine / CH₂Cl₂ / 1 h / 0 °C

3.1: DIBAL-H / tetrahydrofuran; hexane; hexamethylphosphoric acid triamide / 2.5 h / 0 °C

3.2: 82 percent / tetrahydrofuran; hexane; hexamethylphosphoric acid triamide / 0 - 20 °C

4.1: 94 percent / pyridine; DMAP / CH₂Cl₂ / 2 h / 0 °C

With pyridine; dmap; diisobutylaluminium hydride; Dess-Martin periodane; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; dichloromethane;
DOI:10.1021/ja050340q