C₂₇H₂₈ClN₃O₅

Base Information

• Chemical Name: C₂₇H₂₈ClN₃O₅
• CAS No.: 1357089-65-6
• Molecular Formula: C₂₇H₂₈ClN₃O₅
• Molecular Weight: 509.989
• Mol file: 1357089-65-6.mol

Synonyms:C₂₇H₂₈ClN₃O₅

Chemical Property of C₂₇H₂₈ClN₃O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₂₈ClN₃O₅

There total 5 articles about C₂₇H₂₈ClN₃O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

C29H34ClN3O6 (1357089-64-5) → C27H28ClN3O5 (1357089-65-6)

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃; for 3h;

DOI:10.1016/j.bmcl.2011.11.113

Reference yield:

C14H11ClO4 (1357089-61-2) → C27H28ClN3O5 (1357089-65-6)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium tetrahydroborate / methanol / 2 h

2: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 12 h

3: acetic acid; zinc / 2 h

4: lithium hexamethyldisilazane / tetrahydrofuran / 3 h / 0 °C

With sodium tetrahydroborate; di-isopropyl azodicarboxylate; acetic acid; triphenylphosphine; lithium hexamethyldisilazane; zinc; In tetrahydrofuran; methanol;

DOI:10.1016/j.bmcl.2011.11.113

Reference yield:

C29H32ClN3O8 (1357089-63-4) → C27H28ClN3O5 (1357089-65-6)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid; zinc / 2 h

2: lithium hexamethyldisilazane / tetrahydrofuran / 3 h / 0 °C

With acetic acid; lithium hexamethyldisilazane; zinc; In tetrahydrofuran;

DOI:10.1016/j.bmcl.2011.11.113

upstream raw materials:

C₁₄H₁₁ClO₄

C₂₉H₃₂ClN₃O₈

C₂₉H₃₄ClN₃O₆

C₁₄H₁₃ClO₄

Downstream raw materials:

C₂₂H₂₀ClN₃O₃